The SLC2 (GLUT) family of membrane transporters

M Mueckler, B Thorens - Molecular aspects of medicine, 2013 - Elsevier
GLUT proteins are encoded by the SLC2 genes and are members of the major facilitator
superfamily of membrane transporters. Fourteen GLUT proteins are expressed in the human …

Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

CC Barron, PJ Bilan, T Tsakiridis, E Tsiani - Metabolism, 2016 - Elsevier
It is long recognized that cancer cells display increased glucose uptake and metabolism. In
a rate-limiting step for glucose metabolism, the glucose transporter (GLUT) proteins facilitate …

Phosphoinositides: tiny lipids with giant impact on cell regulation

T Balla - Physiological reviews, 2013 - journals.physiology.org
Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

The protein family of glucose transport facilitators: It's not only about glucose after all

R Augustin - IUBMB life, 2010 - Wiley Online Library
The protein family of facilitative glucose transporters comprises 14 isoforms that share
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …

Glucose transporters in brain: in health and in Alzheimer's disease

L Szablewski - Journal of Alzheimer's disease, 2017 - content.iospress.com
Neurons need a continuous supply of glucose, the major source of energy for mammalian
brain metabolism. The central nervous system is protected by three main physiological cell …

Functional properties and genomics of glucose transporters

FQ Zhao, AF Keating - Current genomics, 2007 - ingentaconnect.com
Glucose is the major energy source for mammalian cells as well as an important substrate
for protein and lipid synthesis. Mammalian cells take up glucose from extracellular fluid into …

Pharmacodynamics and pharmacokinetics of inositol (s) in health and disease

M Bizzarri, A Fuso, S Dinicola, A Cucina… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Inositol and its derivatives comprise a huge field of biology. Myo-inositol is not
only a prominent component of membrane-incorporated phosphatidylinositol, but …

Brain glucose transporters: role in pathogenesis and potential targets for the treatment of Alzheimer's disease

L Szablewski - International Journal of Molecular Sciences, 2021 - mdpi.com
The most common cause of dementia, especially in elderly people, is Alzheimer's disease
(AD), with aging as its main risk factor. AD is a multifactorial neurodegenerative disease …

[HTML][HTML] Hepatic expression and cellular distribution of the glucose transporter family

S Karim, DH Adams, PF Lalor - World journal of gastroenterology …, 2012 - ncbi.nlm.nih.gov
Glucose and other carbohydrates are transported into cells using members of a family of
integral membrane glucose transporter (GLUT) molecules. To date 14 members of this …