DNA double-strand breaks (DSBs) disrupt the continuity of chromosomes and their repair by
error-free mechanisms is essential to preserve genome integrity. Microhomology-mediated …

Seeds are important to agriculture and conservation of plant biodiversity. In agriculture, seed
germination performance is an important determinant of crop yield, in particular under …

Orthologs of the yeast telomere protein Stn1 are present in plants, but other components of
the Cdc13/Stn1/Ten1 (CST) complex have only been found in fungi. Here we report the …

The loss of telomere function can result in telomeric fusion events that lead to the types of
genomic rearrangements, such as nonreciprocal translocations, that typify early-stage …

To cope with DNA double strand break (DSB) genotoxicity, cells have evolved two main
repair pathways: homologous recombination which uses homologous DNA sequences as …

Spaceflight-induced changes in astronaut telomeres have garnered significant attention in
recent years. While plants represent an essential component of future long-duration space …

As obligate phototrophs, plants harness energy from sunlight to split water, producing
oxygen and reducing power. This lifestyle exposes plants to particularly high levels of …

DNA damage threatens the integrity of the genome and has potentially lethal consequences
for the organism. Plant DNA is under continuous assault from endogenous and …

The nucleolus is the site of rRNA gene transcription, rRNA processing, and ribosome
biogenesis. However, the nucleolus also plays additional roles in the cell. We isolated …

Abstract The Mre11/Rad50/Nbs1 complex is involved in many aspects of chromosome
metabolism. Aberrant function of the complex is associated with defects in the DNA …