[HTML][HTML] Transcriptional spatial profiling of cancer tissues in the era of immunotherapy: the potential and promise

SN Nerurkar, D Goh, CCL Cheung, PQY Nga, JCT Lim… - Cancers, 2020 - mdpi.com
Simple Summary In recent years, immunotherapy has emerged as a pillar in the fight against
cancer. However, the heterogeneity within the tumor microenvironment poses challenges to …

Preclinical pharmacology modeling of chimeric antigen receptor T therapies

R Kumari, X Ouyang, J Wang, X Xu, M Zheng… - Current Opinion in …, 2021 - Elsevier
Chimeric antigen receptor (CAR) T cells have largely been successful in treating
hematological malignancies in the clinic but have not been as effective in treating solid …