Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research

S Karami-Mohajeri, A Ahmadipour… - Arhiv za higijenu rada i …, 2017 - hrcak.srce.hr
Sažetak Organophosphorus pesticides (OPs) are widely used volatile pesticides that have
harmful effects on the liver in acute and chronic exposures. This review article summarises …

Mitochondrial dysfunction and organophosphorus compounds

S Karami-Mohajeri, M Abdollahi - Toxicology and applied pharmacology, 2013 - Elsevier
Organophosphorous (OPs) pesticides are the most widely used pesticides in the agriculture
and home. However, many acute or chronic poisoning reports about OPs have been …

Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening

Y Koo, BT Hawkins, Y Yun - Scientific reports, 2018 - nature.com
Organophosphate-based compounds (OPs) represent a significant threat to warfighters
(nerve agents) and civilian populations (pesticides). There is a pressing need to develop in …

Betulinic acid induces apoptosis in differentiated PC12 cells via ROS-mediated mitochondrial pathway

X Wang, X Lu, R Zhu, K Zhang, S Li, Z Chen… - Neurochemical research, 2017 - Springer
Betulinic acid (BA), a pentacyclic triterpene of natural origin, has been demonstrated to have
varied biologic activities including anti-viral, anti-inflammatory, and anti-malarial effects; it …

The association between ambient exposure to organophosphates and Parkinson's disease risk

A Wang, M Cockburn, TT Ly, JM Bronstein… - Occupational and …, 2014 - oem.bmj.com
Objectives There is a general consensus that pesticides are involved in the aetiology of
Parkinson's disease (PD), although associations between specific pesticides and the risk of …

Molecular and Cellular Response of Co-cultured Cells toward Cobalt Chloride (CoCl2)-Induced Hypoxia

VK Tripathi, SA Subramaniyan, I Hwang - ACS omega, 2019 - ACS Publications
Cobalt chloride (CoCl2) is a well-known hypoxia mimetic mediator that induces hypoxia-like
responses. CoCl2, a mediator confirmed to alleviate hypoxia-inducible factor-1 (HIF-1), has …

Pesticides as a risk factor for cognitive impairment: Natural substances are expected to become alternative measures to prevent and improve cognitive impairment

L Wen, X Miao, J Ding, X Tong, Y Wu, Y He… - Frontiers in …, 2023 - frontiersin.org
Pesticides are the most effective way to control diseases, insects, weeds, and fungi. The
central nervous system (CNS) is damaged by pesticide residues in various ways. By …

Curcumin revitalizes Amyloid beta (25–35)-induced and organophosphate pesticides pestered neurotoxicity in SH-SY5Y and IMR-32 cells via activation of APE1 and …

B Sarkar, M Dhiman, S Mittal, AK Mantha - Metabolic Brain Disease, 2017 - Springer
Amyloid beta (Aβ) peptide deposition is the primary cause of neurodegeneration in
Alzheimer's disease (AD) pathogenesis. Several reports point towards the role of pesticides …

Tryptophan fluorescence quenching as a binding assay to monitor protein conformation changes in the membrane of intact mitochondria

SMD Akbar, K Sreeramulu, HC Sharma - Journal of bioenergetics and …, 2016 - Springer
Intrinsic protein fluorescence is due to aromatic amino acids, mainly tryptophan, which can
be selectively measured by exciting at 295 nm. Changes in emission spectra of tryptophan …

The potential neurotoxicity of emerging tetrabromobisphenol A derivatives based on rat pheochromocytoma cells

Q Liu, X Ren, Y Long, L Hu, G Qu, Q Zhou, G Jiang - Chemosphere, 2016 - Elsevier
Tetrabromobisphenol A (TBBPA) can cause diverse adverse effects including neurotoxicity.
Emerging TBBPA derivatives, with high structure similarity to the parent compound, are now …