Deep brain stimulation of the thalamus restores signatures of consciousness in a nonhuman primate model

J Tasserie, L Uhrig, JD Sitt, D Manasova, M Dupont… - Science …, 2022 - science.org
Loss of consciousness is associated with the disruption of long-range thalamocortical and
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …

Functional networks in disorders of consciousness

YG Bodien, C Chatelle, BL Edlow - Seminars in neurology, 2017 - thieme-connect.com
Severe brain injury may cause disruption of neural networks that sustain arousal and
awareness, the two essential components of consciousness. Despite the potentially …

Deep brain stimulation for recovery of consciousness in minimally conscious patients after traumatic brain injury: a systematic review

AR Haddad, V Lythe, AL Green - Neuromodulation: Technology at the …, 2019 - Elsevier
Objectives Minimally conscious state (MCS) is a disorder of consciousness in which minimal
but definite behavioral evidence of self-awareness or environmental awareness is …

Disruption in structural–functional network repertoire and time-resolved subcortical fronto-temporoparietal connectivity in disorders of consciousness

R Panda, A Thibaut, A Lopez-Gonzalez, A Escrichs… - Elife, 2022 - elifesciences.org
Understanding recovery of consciousness and elucidating its underlying mechanism is
believed to be crucial in the field of basic neuroscience and medicine. Ideas such as the …

Common data elements for disorders of consciousness: Recommendations from the working group on neuroimaging

BL Edlow, VL Boerwinkle, J Annen, M Boly… - Neurocritical care, 2023 - Springer
Background Over the past 5 decades, advances in neuroimaging have yielded insights into
the pathophysiologic mechanisms that cause disorders of consciousness (DoC) in patients …

[HTML][HTML] Decreased integration of EEG source-space networks in disorders of consciousness

J Rizkallah, J Annen, J Modolo, O Gosseries… - NeuroImage: Clinical, 2019 - Elsevier
Increasing evidence links disorders of consciousness (DOC) with disruptions in functional
connectivity between distant brain areas. However, to which extent the balance of brain …

Whole‐brain analyses indicate the impairment of posterior integration and thalamo‐frontotemporal broadcasting in disorders of consciousness

R Panda, A López‐González, M Gilson… - Human Brain …, 2023 - Wiley Online Library
The study of the brain's dynamical activity is opening a window to help the clinical
assessment of patients with disorders of consciousness. For example, glucose uptake and …

Cerebral electrometabolic coupling in disordered and normal states of consciousness

J Annen, G Frasso, GJM van der Lande, EAC Bonin… - Cell reports, 2023 - cell.com
We assess cerebral integrity with cortical and subcortical FDG-PET and cortical
electroencephalography (EEG) within the mesocircuit model framework in patients with …

Abnormal structural connectivity between the basal ganglia, thalamus, and frontal cortex in patients with disorders of consciousness

L Weng, Q Xie, L Zhao, R Zhang, Q Ma, J Wang… - Cortex, 2017 - Elsevier
Consciousness loss in patients with severe brain injuries is associated with reduced
functional connectivity of the default mode network (DMN), fronto-parietal network, and …

Regional brain volumetry and brain function in severely brain‐injured patients

J Annen, G Frasso, JS Crone, L Heine… - Annals of …, 2018 - Wiley Online Library
Objective The relationship between residual brain tissue in patients with disorders of
consciousness (DOC) and the clinical condition is unclear. This observational study aimed …