The cost of inflammatory bowel disease in high-income settings: a Lancet Gastroenterology & Hepatology Commission

J Burisch, M Zhao, S Odes, P De Cruz… - The Lancet …, 2023 - thelancet.com
The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase
worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease …

Novel small molecules in IBD: current state and future perspectives

A Jefremow, MF Neurath - Cells, 2023 - mdpi.com
Biologicals have dominated the therapeutic scenery in inflammatory bowel diseases (IBDs),
namely ulcerative colitis (UC) and Crohn's disease (CD), for the past 20 years. The …

Efficacy and safety of elective switching from intravenous to subcutaneous infliximab [CT-P13]: a multicentre cohort study

PJ Smith, L Critchley, D Storey, B Gregg… - Journal of Crohn's …, 2022 - academic.oup.com
Background Intravenous [IV] infliximab is a well-established therapy for inflammatory bowel
diseases [IBD] patients. A subcutaneous [SC] formulation of infliximab [CT-P13] has recently …

Is there an optimal sequence of biologic therapies for inflammatory bowel disease?

B Bressler - Therapeutic Advances in Gastroenterology, 2023 - journals.sagepub.com
Over the past two decades, 11 biologic agents have been approved for use in most
countries for the treatment of moderate-to-severe inflammatory bowel disease (IBD) …

Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis

M Attauabi, EK Dahl, J Burisch, J Gubatan… - …, 2023 - thelancet.com
Background Onset of effect of advanced therapies is an important parameter due to
symptom load and risk of disease complications in moderate-to-severe ulcerative colitis …

Classic drugs in the time of new drugs: real‐world, long‐term outcomes of thiopurine monotherapy in 1016 patients with inflammatory bowel disease

A Rezazadeh Ardabili, S Jeuring… - Alimentary …, 2022 - Wiley Online Library
Background Thiopurines remain recommended as maintenance therapy in patients with
inflammatory bowel disease (IBD). Despite their widespread use, long‐term effectiveness …

Biologic therapy for inflammatory bowel disease: Real-world comparative effectiveness and impact of drug sequencing in 13 222 patients within the UK IBD …

C Kapizioni, R Desoki, D Lam… - Journal of Crohn's …, 2024 - academic.oup.com
Abstract Background and Aims This study compares the effectiveness of different biologic
therapies and sequences in patients with inflammatory bowel disease [IBD] using real-world …

Impact of sex and socioeconomic status on the likelihood of surgery, hospitalization, and use of medications in inflammatory bowel disease: a systematic review and …

NF Rasmussen, C Moos, LHK Gregersen, Z Hikmat… - Systematic …, 2024 - Springer
Abstract Background Inflammatory bowel diseases (IBDs) are associated with high
healthcare utilization. This systematic review aimed to summarize what is known about the …

Rising incidence of Pneumocystis pneumonia: a population-level descriptive ecological study in England

K Pates, J Periselneris, MD Russell, V Mehra… - Journal of Infection, 2023 - Elsevier
Objectives Pneumocystis pneumonia (PCP) is an opportunistic infection that causes
significant morbidity and mortality in the immunocompromised population. This population is …

Disease activity patterns of inflammatory bowel disease—A Danish Nationwide Cohort Study 1995–2018

MD Wewer, E Langholz, P Munkholm… - Journal of Crohn's …, 2023 - academic.oup.com
Abstract Background and Aims Few studies have assessed the contemporary patterns of
disease activity in patients with inflammatory bowel disease [IBD]. We aimed to describe the …