Envelope biogenesis and homeostasis in gram-negative bacteria are exceptionally intricate
processes that require a multitude of periplasmic chaperones to ensure cellular survival …

Gram‐negative bacteria are intrinsically resistant against cytotoxic substances by means of
their outer membrane and a network of multidrug efflux systems, acting in synergy. Efflux …

Antibiotics that target Gram-negative bacteria in new ways are needed to resolve the
antimicrobial resistance crisis,–. Gram-negative bacteria are protected by an additional outer …

All Gram-negative bacteria, mitochondria and chloroplasts have outer membrane proteins
(OMPs) that perform many fundamental biological processes. The OMPs in Gram-negative …

Identification of bacterial protein–protein interactions and predicting the structures of these
complexes could aid in the understanding of pathogenicity mechanisms and developing …

The β-barrel assembly machinery (BAM) is a∼ 203 kDa complex of five proteins (BamA–E),
which is essential for viability in E. coli. BAM promotes the folding and insertion of β-barrel …

The outer membrane is a formidable barrier that protects Gram-negative bacteria against
environmental threats. Its integrity requires the correct folding and insertion of outer …

β-barrel membrane proteins perform important functions in the outer membranes (OMs) of
Gram-negative bacteria and of the mitochondria and chloroplasts of eukaryotes. The protein …

The Omp85 protein superfamily is found in the outer membrane (OM) of all gram-negative
bacteria and eukaryotic organelles of bacterial origin. Members of the family catalyze both …

TolC is an archetypal member of the outer membrane efflux protein (OEP) family. These
proteins are involved in export of small molecules and toxins across the outer membrane of …