Growing a circular economy with fungal biotechnology: a white paper

V Meyer, EY Basenko, JP Benz, GH Braus… - Fungal biology and …, 2020 - Springer
Fungi have the ability to transform organic materials into a rich and diverse set of useful
products and provide distinct opportunities for tackling the urgent challenges before all …

Pathogenomics and Management of Fusarium Diseases in Plants

SN Rampersad - Pathogens, 2020 - mdpi.com
There is an urgency to supplant the heavy reliance on chemical control of Fusarium
diseases in different economically important, staple food crops due to development of …

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

J Rhodes, A Abdolrasouli, K Dunne, TR Sewell… - Nature …, 2022 - nature.com
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …

PHI-base: the pathogen–host interactions database

M Urban, A Cuzick, J Seager, V Wood… - Nucleic acids …, 2020 - academic.oup.com
The pathogen–host interactions database (PHI-base) is available at www. phi-base. org. PHI-
base contains expertly curated molecular and biological information on genes proven to …

A Candida auris–specific adhesin, Scf1, governs surface association, colonization, and virulence

DJ Santana, JAE Anku, G Zhao, R Zarnowski… - Science, 2023 - science.org
Candida auris is an emerging fungal pathogen responsible for health care–associated
outbreaks that arise from persistent surface and skin colonization. We characterized the …

PHI-base in 2022: a multi-species phenotype database for pathogen–host interactions

M Urban, A Cuzick, J Seager, V Wood… - Nucleic Acids …, 2022 - academic.oup.com
Abstract Since 2005, the Pathogen–Host Interactions Database (PHI-base) has manually
curated experimentally verified pathogenicity, virulence and effector genes from fungal …

The pan-genome of Aspergillus fumigatus provides a high-resolution view of its population structure revealing high levels of lineage-specific diversity driven by …

LA Lofgren, BS Ross, RA Cramer, JE Stajich - PLoS Biology, 2022 - journals.plos.org
Aspergillus fumigatus is a deadly agent of human fungal disease where virulence
heterogeneity is thought to be at least partially structured by genetic variation between …

A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans

ST Denham, B Brammer, KY Chung, MA Wambaugh… - Cell host & …, 2022 - cell.com
Environmental pathogens move from ecological niches to mammalian hosts, requiring
adaptation to dramatically different environments. Microbes that disseminate farther …

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

C Fu, X Zhang, AO Veri, KR Iyer, E Lash, A Xue… - Nature …, 2021 - nature.com
Fungal pathogens pose a global threat to human health, with Candida albicans among the
leading killers. Systematic analysis of essential genes provides a powerful strategy to …

[HTML][HTML] Plant-microbial endophytes interactions: scrutinizing their beneficial mechanisms from genomic explorations

M del Carmen Orozco-Mosqueda, G Santoyo - Current Plant Biology, 2021 - Elsevier
The study of plant-endophyte interactions is complex and difficult to decipher. In part, this is
because they are dynamic and diverse; these interactions can be mutualistic …