Molecular docking and drug discovery in β-adrenergic receptors
S Vilar, E Sobarzo-Sanchez… - Current medicinal …, 2017 - ingentaconnect.com
Background: Evolution in computer engineering, availability of increasing amounts of data
and the development of new and fast docking algorithms and software have led to improved …
and the development of new and fast docking algorithms and software have led to improved …
The use of GPCR structures in drug design
Abstract Structure-based drug discovery is routinely applied to soluble targets such as
proteases and kinases. It is only recently that multiple high-resolution X-ray structures of G …
proteases and kinases. It is only recently that multiple high-resolution X-ray structures of G …
Adrenoceptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
K Altosaar, P Balaji, RA Bond, DB Bylund… - IUPHAR/BPS Guide …, 2019 - journals.ed.ac.uk
Adrenoceptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Page 1
IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F4/2019.4 …
IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F4/2019.4 …
Norepinephrine protects against methamphetamine toxicity through β2-adrenergic receptors promoting LC3 compartmentalization
G Lazzeri, CL Busceti, F Biagioni, C Fabrizi… - International Journal of …, 2021 - mdpi.com
Norepinephrine (NE) neurons and extracellular NE exert some protective effects against a
variety of insults, including methamphetamine (Meth)-induced cell damage. The intimate …
variety of insults, including methamphetamine (Meth)-induced cell damage. The intimate …
Adrenoceptors in GtoPdb v. 2023.3
JG Baker, P Balaji, RA Bond, DB Bylund… - IUPHAR/BPS Guide …, 2023 - journals.ed.ac.uk
Adrenoceptors in GtoPdb v.2023.3 | IUPHAR/BPS Guide to Pharmacology CITE Skip to main
content Skip to main navigation menu Skip to site footer Journal logo Home Current Archives …
content Skip to main navigation menu Skip to site footer Journal logo Home Current Archives …
Cell-based assays and molecular dynamics analysis of a boron-containing agonist with different profiles of binding to human and guinea pig beta2 adrenoceptors
MA Soriano-Ursúa, M Bello… - European Biophysics …, 2019 - Springer
The design of beta2 adrenoceptor (β 2 AR) agonists is attractive because of their wide-
ranging applications in medicine, and the details of agonist interactions with β 2 AR are …
ranging applications in medicine, and the details of agonist interactions with β 2 AR are …
Advances in theoretical studies on the design of single boron atom compounds
M Bello - Current Pharmaceutical Design, 2018 - ingentaconnect.com
Background: Single Boron Atom Compounds (SBACs) have been used for drug discovery in
diseaseassociated proteins due to the empty p-orbital in the atomic structure of boron, which …
diseaseassociated proteins due to the empty p-orbital in the atomic structure of boron, which …
Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β2-adrenoceptor
MA Soriano-Ursúa, DA McNaught-Flores… - Bioorganic & medicinal …, 2012 - Elsevier
Salbutamol is a well-known β2 adrenoceptor (β2AR) partial agonist. We synthesized two
boron-containing salbutamol derivatives (BCSDs) with greater potency and efficacy …
boron-containing salbutamol derivatives (BCSDs) with greater potency and efficacy …
Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the β2 adrenoceptor
MA Soriano-Ursúa, JA Arias-Montaño… - Bioorganic & Medicinal …, 2015 - Elsevier
The development of β2 adrenoceptor (β 2 AR) agonists is of increasing interest because of
their wide-ranging applications in medicine, particularly for the treatment of pulmonary …
their wide-ranging applications in medicine, particularly for the treatment of pulmonary …
β2-Adrenergic activity of 6-methoxykaempferol-3-O-glucoside on rat uterus: In vitro and in silico studies
6-Methoxykaempferol-3-O-glucoside (6-MKG) was isolated from a Sudanese herb (El-
hazha). The pharmacological effects of 6-MKG were tested on isolated non-pregnant or late …
hazha). The pharmacological effects of 6-MKG were tested on isolated non-pregnant or late …