Protozoan Kinetoplastida, including the pathogenic trypanosomatids of the genera
Trypanosoma and Leishmania, compartmentalize several important metabolic systems in …

A characteristic, well-studied feature of the pathogenic protists belonging to the family
Trypanosomatidae is the compartmentalisation of the major part of the glycolytic pathway in …

Peroxisomes are present in nearly every eukaryotic cell and compartmentalize a wide range
of important metabolic processes. Glycosomes of Kinetoplastid parasites are peroxisome …

The generation of energy in African trypanosomes is a subject of undoubted importance. In
bloodstream-form organisms, substrate-level phosphorylation of glucose is sufficient to …

Inorganic polyphosphate (polyP) is a polymer of three to hundreds of phosphate units bound
by high‐energy phosphoanhydride bonds and present from bacteria to humans. Most polyP …

In Trypanosoma cruzi, the causal agent of Chagas disease, the first seven steps of glycolysis
are compartmentalized in glycosomes, which are authentic but specialized peroxisomes …

Glycosomes are peroxisome-related organelles that have been identified in kinetoplastids
and diplonemids. The hallmark of glycosomes is their harboring of the majority of the …

The causative agent of Chagas disease, Trypanosoma cruzi, metabolizes glucose through
two major pathways: glycolysis and the pentose phosphate pathway. Glucose is taken up via …

In pyrophosphate-dependent glycolysis, the ATP/ADP-dependent enzymes
phosphofructokinase (PFK) and pyruvate kinase are replaced by the pyrophosphate …

Clostridium thermocellum produces ethanol as one of its major end products from direct
fermentation of cellulosic biomass. Therefore, it is viewed as an attractive model for the …