Peptides and proteins have been found to possess an inherent tendency to convert from
their native functional states into intractable amyloid aggregates. This phenomenon is …

Conditions including heating mode, time, temperature, pH, moisture and protein
concentration, shear, and the presence of alcohols, chaotropic/reducing agents, enzymes …

Antibacterial agents with broad-spectrum antibacterial properties have always been in large
demand. Lysozyme, a common and inexpensive protein, is widely used in food safety and …

In this work, we developed β-lactoglobulin nanofibrils by alkaline-thermal activation methods
for Pb removal. The protein fibrils exhibited effective adsorption and selectivity for lead (II) …

Amyloid aggregation of protein is linked to many neurodegenerative diseases. Identification
of small molecules capable of targeting amyloidogenic proteins has gained significant …

Injectable hydrogels based on synthetic peptides have shown great promise in many
biomedical applications. Yet, the high cost generally associated with synthetic peptides …

We use vibrational sum-frequency generation (VSFG) spectroscopy to study the structure of
hen egg-white lysozyme (HEWL) aggregates adsorbed to DOPG/D2O and air/D2O …

Oligomeric intermediates on the pathway of amyloid fibrillation are suspected as the main
cytotoxins responsible for amyloid-related pathogenicity. As they appear to be a part of the …

As manganese ions (Mn2+) are identified as an environmental risk factor for
neurodegenerative diseases, uncovering their action mechanism on protein amyloid fibril …

Thioflavin T (ThT) is widely used as a fluorescent probe for amyloid fibril detection. Yet the
exact kinetic mechanism of ThT binding onto amyloid fibril remains elusive. Previously …