Modulating oxidative stress and neurogenic inflammation: the role of topiramate in migraine treatment

QW Chen, RT Meng, CY Ko - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Migraine is a chronic, recurrent neurovascular disorder characterized by episodes closely
associated with neurovascular hypersensitivity. Oxidative stress can worsen the …

[HTML][HTML] Memantine mitigates ROS/TXNIP/NLRP3 signaling and protects against mouse diabetic retinopathy: Histopathologic, ultrastructural and bioinformatic studies

MH ElSayed, KS Elbayoumi, MA Eladl… - Biomedicine & …, 2023 - Elsevier
Diabetic retinopathy (DRET) triggers vision loss in adults, however, little therapeutic options
are existing. Memantine is an anti-Alzheimer drug that antagonizes the activity of glutamate …

Neuropathic pain in cats: Mechanisms and multimodal management

C Rusbridge - Journal of Feline Medicine and Surgery, 2024 - journals.sagepub.com
Practical relevance: Chronic pain is a significant welfare concern in cats, and neuropathic
pain, which arises from aberrant processing of sensory signals within the nervous system, is …

Protective effect of topiramate against diabetic retinopathy and computational approach recognizing the role of NLRP3/IL-1β/TNF-α signaling

HMF Mohammad, MA Eladl, AKK Abdelmaogood… - Biomedicines, 2023 - mdpi.com
The possible impact of topiramate against diabetic retinopathy (DREN) and its molecular
mechanisms in relation to the nod-like receptor family pyrin domain containing 3 (NLRP3) …

Reduced gastric mucosal nerve density in functional dyspepsia: clinical significance and functional correlation

YC Yang, PH Tseng, CC Chen, YY Cheng… - Official journal of the …, 2022 - journals.lww.com
Background: This study aimed to quantitatively examine gastric mucosal nerve density
(GMND) in patients with functional dyspepsia (FD) and analyzed its clinical correlation …