Autophagy and autophagy‐related processes are fundamentally important in human health
and disease. These processes are viewed primarily as cellular degradative pathways that …

Glioblastoma (GB) is the most malignant of primary adult brain tumors, characterized by a
highly locally invasive cell population, as well as abundant proliferative cells …

Cannabinoids are known to modulate oligodendrogenesis and developmental CNS
myelination. However, the cell-autonomous action of these compounds on oligodendroglial …

Cytotoxic necrotizing factor 1 (CNF1) is a bacterial virulence factor, the target of which is
represented by Rho GTPases, small proteins involved in a huge number of crucial cellular …

Orofacial clefts (OFCs) represent a large fraction of human birth defects and are one of the
most common phenotypes affected by large copy number variants (CNVs). Due to the limited …

Growing evidence indicates that overproduction of reactive oxygen species (ROS) plays a
prominent role in the development of cardio-and cerebro-vascular diseases. Among the …

Cerebral cavernous malformation (CCM) involves the homozygous inactivating mutations of
one of three genes, ccm1,-2, or-3 resulting in hyperpermeable blood vessels in the brain …

Protein ubiquitination is an important post-translational modification that is associated with
multiple diseases, including pituitary adenomas (PAs). Protein ubiquitination profiling in …

Background Cell migration is essential for development and tissue repair, but it also
contributes to disease. Rho GTPases regulate cell migration, but a comprehensive analysis …

The involvement of Rho of Plants (ROP) GTP ases in abscisic acid (ABA) signalling in
Arabidopsis has been demonstrated in many studies. However, the roles of Rop GEF s (Rop …