Monitoring eye movement in patients with Parkinson's disease: what can it tell us?

YR Sun, SB Beylergil, P Gupta, FF Ghasia… - Eye and …, 2023 - Taylor & Francis
Parkinson's disease (PD) affects approximately 10 million individuals worldwide. Visual
impairments are a common feature of PD. Patients report difficulties with visual scanning …

Strabismus and the oculomotor system: insights from macaque models

VE Das - Annual review of vision science, 2016 - annualreviews.org
Disrupting binocular vision in infancy leads to strabismus and oftentimes to a variety of
associated visual sensory deficits and oculomotor abnormalities. Investigation of this …

Neural control of rapid binocular eye movements: Saccade-vergence burst neurons

J Quinet, K Schultz, PJ May… - Proceedings of the …, 2020 - National Acad Sciences
During normal viewing, we direct our eyes between objects in three-dimensional (3D) space
many times a minute. To accurately fixate these objects, which are usually located in …

Abnormal fixational eye movements in strabismus

FF Ghasia, J Otero-Millan, AG Shaikh - British Journal of …, 2018 - bjo.bmj.com
Introduction Fixational saccades are miniature eye movements that constantly change the
gaze during attempted visual fixation. Visually guided saccades and fixational saccades …

A central mesencephalic reticular formation projection to the Edinger–Westphal nuclei

PJ May, S Warren, MO Bohlen, M Barnerssoi… - Brain Structure and …, 2016 - Springer
The central mesencephalic reticular formation, a region associated with horizontal gaze
control, has recently been shown to project to the supraoculomotor area in primates. The …

A central mesencephalic reticular formation projection to medial rectus motoneurons supplying singly and multiply innervated extraocular muscle fibers

MO Bohlen, S Warren, PJ May - Journal of Comparative …, 2017 - Wiley Online Library
We recently demonstrated a bilateral projection to the supraoculomotor area from the central
mesencephalic reticular formation (cMRF), a region implicated in horizontal gaze changes …

Vergence and strabismus in neurodegenerative disorders

SL Kang, AG Shaikh, FF Ghasia - Frontiers in neurology, 2018 - frontiersin.org
Maintaining proper eye alignment is necessary to generate a cohesive visual image. This
involves the coordination of complex neural networks, which can become impaired by …

Muscimol inactivation of caudal fastigial nucleus and posterior interposed nucleus in monkeys with strabismus

AC Joshi, VE Das - Journal of neurophysiology, 2013 - journals.physiology.org
Previously, we showed that neurons in the supraoculomotor area (SOA), known to encode
vergence angle in normal monkeys, encode the horizontal eye misalignment in strabismic …

Autonomic regulation of the eye

PJ May, A Reiner, PD Gamlin - Oxford research encyclopedia of …, 2019 - oxfordre.com
The functions of the eye are regulated by and dependent upon the autonomic nervous
system. The parasympathetic nervous system controls constriction of the iris and …

Neural mechanisms of oculomotor abnormalities in the infantile strabismus syndrome

MMG Walton, A Pallus, J Fleuriet… - Journal of …, 2017 - journals.physiology.org
Infantile strabismus is characterized by numerous visual and oculomotor abnormalities.
Recently nonhuman primate models of infantile strabismus have been established, with …