Circuits and functions of the lateral habenula in health and in disease

H Hu, Y Cui, Y Yang - Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …

The habenula: from stress evasion to value-based decision-making

O Hikosaka - Nature reviews neuroscience, 2010 - nature.com
Surviving in a world with hidden rewards and dangers requires choosing the appropriate
behaviours. Recent discoveries indicate that the habenula plays a prominent part in such …

The cholinergic system, circadian rhythmicity, and time memory

RA Hut, EA Van der Zee - Behavioural brain research, 2011 - Elsevier
This review provides an overview of the interaction between the mammalian cholinergic
system and circadian system, and its possible role in time memory. Several studies made …

The lateral habenula and adaptive behaviors

SJY Mizumori, PM Baker - Trends in neurosciences, 2017 - cell.com
The evolutionarily conserved lateral habenula (LHb) enables dynamic responses to
continually changing contexts and environmental conditions. A model is proposed to …

Complex relationships of nicotinic receptor actions and cognitive functions

ED Levin - Biochemical pharmacology, 2013 - Elsevier
Nicotine has been shown in a variety of studies to improve cognitive function including
learning, memory and attention. Nicotine both stimulates and desensitizes nicotinic …

Role of glutamatergic projections from lateral habenula to Ventral Tegmental Area in Inflammatory Pain-related spatial Working Memory deficits

M Alemi, AR Pereira, M Cerqueira-Nunes, C Monteiro… - Biomedicines, 2023 - mdpi.com
The lateral habenula (LHb) and the ventral tegmental area (VTA), which form interconnected
circuits, have important roles in the crucial control of sensory and cognitive motifs. Signaling …

The lateral habenula as a relay of cortical information to process working memory

V Mathis, A Barbelivien, M Majchrzak, C Mathis… - Cerebral …, 2017 - academic.oup.com
Working memory is a cognitive ability allowing the temporary storage of information to solve
problems or adjust behavior. While working memory is known to mainly depend on the …

Daily variation in the electrophysiological activity of mouse medial habenula neurones

K Sakhi, MDC Belle, N Gossan… - The Journal of …, 2014 - Wiley Online Library
Key points Neurones of the suprachiasmatic nucleus (SCN) contain a molecular clock that
drives these cells to exhibit daily rhythms in electrical activity. The molecular clock may also …

A comparison of mecamylamine and bupropion effects on memory-related responses induced by nicotine and scopolamine in the novel object recognition test in mice

M Kruk-Słomka, A Michalak, B Budzyńska… - Pharmacological …, 2014 - Elsevier
Background The aim of the present study was to evaluate the involvement of the cholinergic
receptors ligands in the memory-related responses in mice, using the novel object …

α7-Nicotinic acetylcholine receptors: an old actor for new different roles

P Russo, A Taly - Current Drug Targets, 2012 - ingentaconnect.com
7-Nicotinic Acetylcholine Receptors: An Old Actor for New Different Roles Page 1 574 Current
Drug Targets, 2012, 13, 574-578 1873-5592/12 $58.00+.00 © 2012 Bentham Science Publishers …