Evaluation of Single Dose and Fractionated Dose of I-131 Radiolabeled Nanoparticles for Triple-Negative Breast Cancer Treatment

SK Marshall, N Kaewpradit, T Mudmarn, J Buathong… - Biomedicines, 2023 - mdpi.com
Combination chemotherapy is still the standard clinical care for triple-negative breast cancer
(TNBC). However, sodium iodide symporter (NIS) uptake by TNBC has opened the potential …

[HTML][HTML] Appraisal of radioiodine refractory thyroid cancer: advances and challenges

H Liu, D Yang, L Li, Y Tu, C Chen… - American Journal of …, 2020 - ncbi.nlm.nih.gov
The incidence of thyroid cancer ranks top among all endocrine cancers, which has
increased worldwide. Some patients suffer from recurrent/residual diseases after primary …

Anti-EpCAM functionalized I-131 radiolabeled biomimetic nanocarrier sodium/iodide-symporter-mediated breast-cancer treatment

SK Marshall, Y Panrak, N Makchuchit, P Jaroenpakdee… - Bioengineering, 2022 - mdpi.com
Currently, breast-cancer treatment has a number of adverse side effects and is associated
with poor rates of progression-free survival. Therefore, a radiolabeled anti-EpCAM targeted …

Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma

H Rakhsh-Khorshid, H Samimi, S Torabi… - Scientific Reports, 2020 - nature.com
Anaplastic thyroid carcinoma (ATC) is the most rare and lethal form of thyroid cancer and
requires effective treatment. Efforts have been made to restore sodium-iodide symporter …

Poly (lactic-co-glycolic acid)-encapsulated iodine-131 nanoparticles fabricated with rhTSH induce apoptosis and immobilization of thyroid cancer cells

Y Fan, Y Xiong, X Wang, J Chen, D Fang… - Frontiers in …, 2023 - frontiersin.org
Background Aggressive thyroid carcinoma (ATC) usually loses radioiodine avidity to iodine-
131 (131I) due to the downregulation of sodium/iodide symporter (NIS). The expression of …

Reporter PET images bortezomib treatment-mediated suppression of cancer cell proteasome activity

JH Lee, KH Jung, CHT Quach, JW Park, SH Moon… - Scientific Reports, 2018 - nature.com
Proteasomal protein degradation is a promising target for cancer therapy. Here, we
developed a positron emission tomography (PET) technique based on the sodium-iodide …

[引用][C] 分化型甲状腺癌NIS 与TSHR 研究进展

茹晓婷, 刘勤江, 杨荣 - 甘肃医药, 2016