Muscle glycogen is the main substrate during high-intensity exercise and large reductions
can occur after relatively short durations. Moreover, muscle glycogen is stored …

Abstract Clausen, Torben. Na+-K+ Pump Regulation and Skeletal Muscle Contractility.
Physiol Rev 83: 1269-1324, 2003; 10.1152/physrev. 00011.2003.—In skeletal muscle …

Lactate or gas exchange threshold (GET) and critical power (CP) are closely associated with
human exercise performance. We tested the hypothesis that the limit of tolerance (Tlim) …

Much of the previous research into understanding fatigue during prolonged cycling has
found that cycling performance may be limited by numerous physiological, biomechanical …

This review addresses cerebral metabolic and neurohumoral alterations during prolonged
exercise in humans with special focus on associations with fatigue. Global energy turnover …

Purpose: Few studies have assessed neuromuscular fatigue after self-paced locomotor
exercise; moreover, none have assessed the degree of supraspinal fatigue. This study …

Skeletal muscle fatigue is defined as the fall of force or power in response to contractile
activity. Both the mechanisms of fatigue and the modes used to elicit it vary tremendously …

Membrane excitability is a critical regulatory step in skeletal muscle contraction and is
modulated by local ionic concentrations, conductances, ion transporter activities …

Reactive oxygen species (ROS) have been linked with both depressed Na+, K+‐pump
activity and skeletal muscle fatigue. This study investigated N‐acetylcysteine (NAC) effects …

Key points• Processes leading to fatigue occur within the exercising muscle (peripheral
fatigue) and the nervous system (central fatigue).• We asked whether central processes of …