Dengue fever is a dangerous infectious endemic disease that affects over 100 nations
worldwide, from Africa to the Western Pacific, and is caused by the dengue virus, which is …

Background. Breast cancer is one of the most common types of cancer diagnosed and the
second leading cause of death among women. Breast cancer susceptibility proteins of type …

ABSTRACT Background The African continent is home to five biodiversity hotspots, boasting
an immense wealth of medicinal flora, fungi and marine life. Diterpenes extracted from such …

Abstract Background Traditional Chinese medicine (TCM) is regarded as a large database
containing hundreds to thousands of chemical constituents that can be further developed as …

Aleuritopteris argentea (SG Gmél.) Fée is a medicinal fern, the main metabolite of which is
an ent-labdane diterpene, ie, alepterolic acid. Previous studies showed that this compound …

Ferns are vascular plants that have been extensively studied in recent decades for their
phytochemical and anticancer activities. Polypodiales is an order of ferns consisting of 26 …

Alepterolic acid is a diterpene occurring in the fern Aleuritopteris argentea with potential
biological activity that warrants further structural modification. In the present work, sixteen …

Alepterolic acid is a natural diterpenoid isolated from Aleuritopteris argentea with potential
anti‐cancer activity. In this study, alepterolic acid was modified to construct a series of …

A new pimarane-type diterpene, ent-8 (14), 15-pimaradiene-2 β, 19-diol (JXE-23), was
isolated from the fern plant Aleuritopteris albofusca by our previous work; however, the …

An ent-pimaradiene diterpene, ent-8 (14), 15-pimaradiene-2β, 19-diol (1), and a cyathane
diterpene, 14-oxy-7α, 20-dihydroxycyath-12, 18-diene (2), together with seven known …