Probing the links: Long non-coding RNAs and NF-κB signalling in atherosclerosis

MS Hussain, O Afzal, G Gupta, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …

The pathophysiological role of CoA

A Czumaj, S Szrok-Jurga, A Hebanowska… - International Journal of …, 2020 - mdpi.com
The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …

[HTML][HTML] MicroRNAs as biological regulators in skin disorders

G Singhvi, P Manchanda, VK Rapalli, SK Dubey… - Biomedicine & …, 2018 - Elsevier
Abstract microRNAs are being investigated as promising therapeutic targets and biomarkers
for different disease conditions. miRNAs serve as essential regulators of cell differentiation …

Could IL-17A be a novel therapeutic target in diabetic nephropathy?

C Lavoz, S Rayego-Mateos, M Orejudo… - Journal of clinical …, 2020 - mdpi.com
Chronic kidney disease has become a major medical issue in recent years due to its high
prevalence worldwide, its association with premature mortality, and its social and economic …

LncRNAs and PTEN/PI3K signaling: A symphony of regulation in cancer biology

WH Almalki - Pathology-Research and Practice, 2023 - Elsevier
Abstract The Emergence of Long Non-coding RNAs (lncRNAs) as Key Regulators in Diverse
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …

Exploring GAS5's impact on prostate cancer: Recent discoveries and emerging paradigms

KS Alharbi - Pathology-Research and Practice, 2023 - Elsevier
Novel treatment targets must be discovered to improve the results for patients with prostate
cancer, which continues to be a significant worldwide health problem. Growth Arrest-Specific …

Therapeutic potential of miRNAs for type 2 diabetes mellitus: an overview

P Palihaderu, B Mendis, J Premarathne… - Epigenetics …, 2022 - journals.sagepub.com
MicroRNA (miRNA) s have been identified as an emerging class for therapeutic
interventions mainly due to their extracellularly stable presence in humans and animals and …

Introduction to epigenetics

N Singla, R Thapa, R Kulshrestha, AA Bhat… - Targeting epigenetics in …, 2023 - Springer
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …

Elevation of circulating miR‐210 participates in the occurrence and development of type 2 diabetes mellitus and its complications

X Chen, F Tian, Z Sun, G Zeng… - Journal of Diabetes …, 2022 - Wiley Online Library
Objective. Circulating miRNAs are acclaimed biomarkers to predict the occurrence and
progression of type 2 diabetes mellitus (T2DM). This study is aimed at analyzing the …

Polygonatum sibiricum polysaccharides (PSP) improve the palmitic acid (PA)-induced inhibition of survival, inflammation, and glucose uptake in skeletal muscle cells

JL Cai, XP Li, YL Zhu, GQ Yi, W Wang, XY Chen… - …, 2021 - Taylor & Francis
Polygonatum sibiricum polysaccharides (PSP) can decrease the levels of fasting blood
glucose, total cholesterol, and triglyceride (TG) in hyperlipidemic and diabetic animals. It can …