Recent progress in the development of fluorescent probes for imaging pathological oxidative stress
Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …
Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease
LP Dolgacheva, AV Berezhnov, EI Fedotova… - Journal of Bioenergetics …, 2019 - Springer
DJ-1 protein has multiple specific mechanisms to protect dopaminergic neurons against
neurodegeneration in Parkinson's disease. Wild type DJ-1 can acts as oxidative stress …
neurodegeneration in Parkinson's disease. Wild type DJ-1 can acts as oxidative stress …
Unique functional responses differentially map onto genetic subtypes of dopamine neurons
Dopamine neurons are characterized by their response to unexpected rewards, but they
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …
Locus coeruleus
EE Benarroch - Cell and tissue research, 2018 - Springer
The locus coeruleus (LC) contains norepinephrine (NE)-synthesizing neurons that send
diffuse projections throughout the central nervous system. The LC-NE system has a major …
diffuse projections throughout the central nervous system. The LC-NE system has a major …
Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic …
J Peris, K MacFadyen, JA Smith… - Journal of …, 2017 - Wiley Online Library
The mesolimbic dopamine (DA) circuitry determines which behaviors are positively
reinforcing and therefore should be encoded in the memory to become a part of the …
reinforcing and therefore should be encoded in the memory to become a part of the …
Efficient detection of Parkinson's disease using deep learning techniques over medical data
Parkinson's disease is a degenerative disease that leads to brain disorder and
nonfunctioning of different body parts. Deep learning tools like artificial neural network …
nonfunctioning of different body parts. Deep learning tools like artificial neural network …
[HTML][HTML] Axonal damage and loss of connectivity in nigrostriatal and mesolimbic dopamine pathways in early Parkinson's disease
A progressive loss of dopamine neurons in the substantia nigra (SN) is considered the main
feature of idiopathic Parkinson's disease (PD). Recent neuropathological evidence however …
feature of idiopathic Parkinson's disease (PD). Recent neuropathological evidence however …
[HTML][HTML] Molecular heterogeneity in the substantia nigra: A roadmap for understanding PD motor pathophysiology
As the ability to capture single-cell expression profiles has grown in recent years,
neuroscientists studying a wide gamut of brain regions have discovered remarkable …
neuroscientists studying a wide gamut of brain regions have discovered remarkable …
In vivo functional diversity of midbrain dopamine neurons within identified axonal projections
Functional diversity of midbrain dopamine (DA) neurons ranges across multiple scales, from
differences in intrinsic properties and connectivity to selective task engagement in behaving …
differences in intrinsic properties and connectivity to selective task engagement in behaving …
Functional neuroanatomical review of the ventral tegmental area
The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are assumed to
play a key role in dopamine-related functions such as reward-related behaviour, motivation …
play a key role in dopamine-related functions such as reward-related behaviour, motivation …