[HTML][HTML] Recent treatment strategies and molecular pathways in resistance mechanisms of antiangiogenic therapies in glioblastoma

MA Rahman, MM Ali - Cancers, 2024 - mdpi.com
Simple Summary Glioblastoma (GBM) appears to be a challenging malignancy to
completely eradicate, with few significant improvements in treatment. This review explores …

Overcoming Resistance to Temozolomide in Glioblastoma: A Scoping Review of Preclinical and Clinical Data

D Smerdi, M Moutafi, I Kotsantis, LC Stavrinou, A Psyrri - Life, 2024 - mdpi.com
Glioblastoma (GB) is the most common and most aggressive primary brain tumor in adults,
with an overall survival almost 14.6 months. Optimal resection followed by combined …

Heterogeneous biomechanical/mathematical modeling of spatial prediction of glioblastoma progression using magnetic resonance imaging-based finite element …

MR Ghahramani, O Bavi - Computer Methods and Programs in …, 2024 - Elsevier
Abstract Background and Objective Brain tumors are one of the most common diseases and
causes of death in humans. Since the growth of brain tumors has irreparable risks for the …

AT-0174, a novel dual IDO1/TDO2 enzyme inhibitor, synergises with temozolomide to improve survival in an orthotopic mouse model of glioblastoma

MJ Bickerdike, I Nafia, A Bessede, CB Chen… - BMC cancer, 2024 - Springer
Background Glioblastoma is an aggressive brain cancer, usually of unknown etiology, and
with a very poor prognosis. Survival from diagnosis averages only 3 months if left untreated …

Role of Wnt/β-catenin pathway in cancer drug resistance: Insights into molecular aspects of major solid tumors

C Samant, R Kale, KSR Pai, K Nandakumar… - Biochemical and …, 2024 - Elsevier
Adaptive resistance to conventional and targeted therapies remains one of the major
obstacles in effective management of cancer. Aberrant activation of key signaling …

Prospects of marine-derived compounds as potential therapeutic agents for glioma

Y Liu, Z Zhou, S Sun - Pharmaceutical Biology, 2024 - Taylor & Francis
Context Glioma, the most common primary malignant brain tumour, is a grave health
concern associated with high morbidity and mortality. Current treatments, while effective to …

Circular RNAs in glioblastoma

E Ghadami, M Jafari, M Razipour, M Maghsudlu… - Clinica Chimica …, 2024 - Elsevier
Glioblastoma multiforme (GBM) is the most malignant and common form of brain cancer in
adults. The molecular mechanisms underlying GBM progression and resistance are …

Fabrication of temozolomide-loaded polydopamine-coated copper ferrite clocked bovine serum albumin nanoparticles delivery for glioma cancer and induction of …

C Zhu, H Chen, Z Chen, M Yang, H Wang, Q Li… - Journal of Drug Delivery …, 2025 - Elsevier
Chemodynamic therapy (CDT) refers to producing a substantial quantity of reactive oxygen
species (ROS) within tumor tissue using a nanocatalyst based on the Fenton reaction. This …

[HTML][HTML] Comprehensive insight into 3D bioprinting technology for brain tumor modelling

A Kim, K Mo, S Choe, M Shin… - International Journal of …, 2024 - accscience.com
Glioblastoma is one of the most common primary malignant brain tumors with a poor
prognosis and high mortality rate. Since only small lipophilic molecules can penetrate the …

Evaluation of Microvascular Density in Glioblastomas in Relation to p53 and Ki67 Immunoexpression

TC Sipos, A Kövecsi, L Kocsis, M Nagy-Bota… - International Journal of …, 2024 - mdpi.com
Glioblastoma is the most aggressive tumor in the central nervous system, with a survival rate
of less than 15 months despite multimodal therapy. Tumor recurrence frequently occurs after …