In mammals, phosphate balance is maintained by influx and efflux via the intestines,
kidneys, bone, and soft tissue, which involves multiple sodium/phosphate (Na+/Pi) …

Primary familial brain calcification (PFBC), also known as Fahr's disease, is a rare inherited
disorder characterized by bilateral calcification in the basal ganglia according to …

Introduction There are now a number genes, known to be associated with familial primary
brain calcification (PFBC), causing the so called 'Fahr's' disease or syndrome. These are …

Phosphate is essential for skeletal mineralization, and its chronic deficiency leads to rickets
and osteomalacia. Skeletal mineralization starts in matrix vesicles (MVs) derived from the …

Primary Familial Brain Calcification (PFBC) is a dominantly inherited cerebral microvascular
calcifying disorder with diverse neuropsychiatric expression. Three causative genes have …

Trace elements, such as iron, copper, manganese, and calcium, which are essential
constituents necessary for cellular homeostasis, become toxic when present in excess …

Primary familial brain calcification (PFBC) is a rare cerebral microvascular calcifying
disorder with a wide spectrum of motor, cognitive, and neuropsychiatric symptoms. It is …

Primary familial brain calcification (PFBC) is a heterogeneous neuropsychiatric disorder,
with affected individuals presenting a wide variety of motor and cognitive impairments, such …

Idiopathic basal ganglia calcification is a brain calcification disorder that has been
genetically linked to autosomal dominant mutations in the sodium‐dependent phosphate co …

Antipsychotic agents, also termed neuroleptics or dopamine-receptor blocking agents
(DBAs), are extensively utilized in the management of psychiatric disorders such as …