Interleukin‐8 (IL‐8) belongs to a family of small, structurally related cytokines similar to
platelet factor 4. It is produced by phagocytes and mesenchymal cells exposed to …

Publisher Summary This chapter focuses on interleukin-8 (IL-8) and related chemotactic
cytokines—namely, CXC and CC chemokines. IL-8 is the best known member of a new …

Human γδ T cells are considered to play a vital role in protective immunity through cytokine
secretion and cytotoxic activity. We report that cells expressing the Vγ2Vδ2+–T cell receptor …

Phosphatidylinositol 3, 4, 5-trisphosphate (PtdInsP3) is rapidly produced upon exposure of
neutrophils to the chemoattractant N-formylmethionyl-leucylphenylalanine (fMLP), and has …

Chemoattractants and chemokines, such as interleukin 8 (IL-8), are defined by their ability to
induce directed cell migration of responsive cells. The signal transduction pathway (s) …

Interleukin-8 (IL-8), the prototypic member of the CXC subfamily of chemokines, induces in
neutrophils chemotaxis, the respiratory burst, granule release, and increased cell adhesion …

This study was undertaken to analyze how cell binding to extracellular matrix produces
changes in cell shape. We focused on the initial process of cell spreading that follows cell …

The mechanical properties of cytoplasm are dominated by microfilaments, microtubules, and
intermediate filaments, collectively termed the cytoskeleton. This review discusses how the …

The neutrophils constitute the largest population of white blood cells and the first line of
defense of mammalian organisms against invading microbes. They circulate passively in the …

The deregulation of inflammatory response during sepsis seems to reflect the
overproduction of mediators, which suppress leukocyte functions. We investigated the …