Mesenchymal stem cell derived extracellular vesicles for tissue engineering and regenerative medicine applications

D Tsiapalis, L O'Driscoll - Cells, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in
tissue engineering and regenerative medicine. However, recent evidence suggests that the …

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble …

R Mitchell, B Mellows, J Sheard, M Antonioli… - Stem cell research & …, 2019 - Springer
Background The mechanisms underpinning the regenerative capabilities of mesenchymal
stem cells (MSC) were originally thought to reside in their ability to recognise damaged …

Mesenchymal stromal cells and their secretome: new therapeutic perspectives for skeletal muscle regeneration

M Sandonà, L Di Pietro, F Esposito… - … in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Skeletal muscle regeneration in cardiotoxin-induced muscle injury models

Y Wang, J Lu, Y Liu - International journal of molecular sciences, 2022 - mdpi.com
Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …

Anti‐arthritic effect of chicken embryo tissue hydrolyzate against adjuvant arthritis in rats (X‐ray microtomographic and histopathological analysis)

I Rzhepakovsky, S Anusha Siddiqui… - Food Science & …, 2021 - Wiley Online Library
Finding new, safe strategies to prevent and control rheumatoid arthritis is an urgent task.
Bioactive peptides and peptide‐rich protein hydrolyzate represent a new trend in the …

Mesenchymal stem cell-derived extracellular vesicles: regenerative potential and challenges

S Fuloria, V Subramaniyan, R Dahiya, S Dahiya… - Biology, 2021 - mdpi.com
Simple Summary Mesenchymal stem cell extracellular vesicles (MSCEVs) obtained from
MSCs can have numerous therapeutic applications via regeneration of various body tissues …

Fetal lung underdevelopment is rescued by administration of amniotic fluid stem cell extracellular vesicles in rodents

L Antounians, VD Catania, L Montalva, BD Liu… - Science Translational …, 2021 - science.org
Fetal lung underdevelopment, also known as pulmonary hypoplasia, is characterized by
decreased lung growth and maturation. The most common birth defect found in babies with …

Uncovering the gray zone: mapping the global landscape of direct-to-consumer businesses offering interventions based on secretomes, extracellular vesicles, and …

A Asadpour, BH Yahaya, K Bicknell, GS Cottrell… - Stem Cell Research & …, 2023 - Springer
Background The last decade has seen a significant increase in media attention, industrial
growth, and patient interest in stem cell-based interventions. This led to a rise in direct-to …

Extracellular vesicles from mesenchymal stem cells as novel treatments for musculoskeletal diseases

MJ Alcaraz, A Compañ, MI Guillén - Cells, 2019 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) represent a promising therapy for musculoskeletal
diseases. There is compelling evidence indicating that MSC effects are mainly mediated by …