Melorheostosis: a rare sclerosing bone dysplasia

A Kotwal, BL Clarke - Current osteoporosis reports, 2017 - Springer
Abstract Purpose of Review Melorheostosis is a rare sclerosing bone dysplasia that affects
both cortical bone and adjacent soft tissue structures in a sclerotomal distribution. In this …

Melorheostosis and osteopoikilosis: a review of clinical features and pathogenesis

P Wordsworth, M Chan - Calcified tissue international, 2019 - Springer
Melorheostosis is an exceptionally rare sclerosing hyperostosis that typically affects the
appendicular skeleton in a limited segmental fashion. It occasionally occurs on a …

Sclerosing bone disorders

MP Whyte - Primer on the metabolic bone diseases and …, 2013 - Wiley Online Library
This chapter focuses on sclerosing bone disorders such as osteopetrosis, carbonic
anhydrase II deficiency, progressive diaphyseal dysplasia (Camurati‐Engelmann Disease) …

Sclerodermalike syndromes: great imitators

C Varjú, G Kumánovics, L Czirják… - Clinics in …, 2020 - Elsevier
Sclerodermalike syndromes (SLSs) comprise diseases with mucin deposition (eg,
scleromyxedema, scleredema), with eosinophilia (eg, eosinophilic fasciitis), metabolic or …

Melorheostosis: a clinical, pathologic, and radiologic case series

CN Fick, N Fratzl-Zelman, P Roschger… - The American journal …, 2019 - journals.lww.com
Melorheostosis is a rare sclerosing bone disease characterized by excessive cortical bone
deposition that is frequently on the differential diagnosis for bone biopsies. Although the …

The dripping candle wax sign of melorheostosis

VT Hoang, HAT Van… - SAGE Open Medical …, 2020 - journals.sagepub.com
Melorheostosis is a rare benign bone disease including dysostosis and sclerosis. Dripping
candle wax presence is a common and typical sign of melorheostosis. This sign appears as …

Melorheostotic Bone Lesions Caused by Somatic Mutations in MAP2K1 Have Deteriorated Microarchitecture and Periosteal Reaction

N Fratzl‐Zelman, P Roschger, H Kang… - Journal of Bone and …, 2019 - academic.oup.com
Melorheostosis is a rare non‐hereditary condition characterized by dense hyperostotic
lesions with radiographic “dripping candle wax” appearance. Somatic activating mutations in …

Clinical improvement in a patient with monostotic melorheostosis after treatment with denosumab: a case report

S Byberg, B Abrahamsen, M Kassem, S Ralston… - Journal of medical case …, 2018 - Springer
Background A 20-year-old Danish woman with melorheostosis in her right femoral shaft and
disabling pain in the affected area, whose symptoms did not in the long term respond to …

A focus on melorheostosis disease: a literature review and case report of femoral-acetabular impingement due to melorheostosis treated with surgical hip osteoplasty

M Ruggiero, A Conforti, A Culcasi, C Mazzanti… - Reumatismo, 2024 - reumatismo.org
Objective. Melorheostosis is a rare, non-hereditary, benign bone disease characterized by
abnormal bone growth. Generally, melorheostosis develops during childhood or …

Unraveling melorheostosis: insights into clinical features, diagnosis, and treatment

T Bhattacharyya - JBMR plus, 2025 - academic.oup.com
Melorheostosis is a rare bone disease characterized by abundant bone formation with a
characteristic radiographic appearance that resembles “dripping candle wax.” Recent data …