Most eukaryotes require oxygen for their survival and, with increasing multicellular
complexity, oxygen availability and delivery rates vary across the tissues of complex …

Wogonin is a flavonoid found in different plants such as roots of Scutellaria baicalensis
Georgi distributed mainly in Asia and Europe. Dried root extracts of S. baicalensis with high …

Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the nasal cavity
characterized by excessive nasal mucus secretion and nasal congestion. The development …

Nasal polyps, as a subtype of chronic sinusitis, is prone to clinical recurrence and seriously
affects the quality of life of patients, but its pathogenesis is unclear. It is considered to be a …

In chronic upper respiratory tract diseases, increased cell proliferative activity is observed,
which is coordinated by BCL-2 proteins and small non-coding RNAs. This study aimed to …

Purpose Osteitis refers to the development of new bone formation and remodeling of bone in
chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal …

Chronic rhinosinusitis (CRS) is a multifactorial and highly heterogeneous upper airway
disease that affects approximately 12% of the general population. There is increasing …

Background Severe neutrophilic asthma is often characterized by persistent airway
inflammation and irreversible airway remodeling, which are overstimulated by the high …

Mucus secretion and its composition are vital in the maintenance of airway health, among
which hypoxia-inducible factors (HIFs) are thought to be involved in the regulation of mucin …

Endocrine disrupting chemicals have been known to contribute to the aggravation of
inflammatory diseases including asthma. We aimed to investigate the effects of mono‐n …