Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

The spectrum of MALT lymphoma at different sites: biological and therapeutic relevance

E Zucca, F Bertoni - Blood, The Journal of the American Society …, 2016 - ashpublications.org
Extranodal marginal zone (MZ) B-cell lymphomas of the mucosa-associated lymphoid tissue
(MALT) arise from lymphoid populations that are induced by chronic inflammation in …

Oncogenic activation of NF-κB

LM Staudt - Cold Spring Harbor perspectives in biology, 2010 - cshperspectives.cshlp.org
Recent genetic evidence has established a pathogenetic role for NF-κB signaling in cancer.
NF-κB signaling is engaged transiently when normal B lymphocytes respond to antigens, but …

Immune therapy for cancer

M Dougan, G Dranoff - Annual review of immunology, 2009 - annualreviews.org
Over the past decade, immune therapy has become a standard treatment for a variety of
cancers. Monoclonal antibodies, immune adjuvants, and vaccines against oncogenic …

EGILS consensus report. Gastric extranodal marginal zone B-cell lymphoma of MALT

A Ruskoné-Fourmestraux, W Fischbach, BMP Aleman… - Gut, 2011 - gut.bmj.com
This consensus report of the EGILS (European Gastro-Intestinal Lymphoma Study) group
includes recommendations on the management of gastric extranodal marginal zone B-cell …

Long-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori: a multicentre cohort follow-up study of 420 patients in Japan

S Nakamura, T Sugiyama, T Matsumoto, K Iijima… - Gut, 2012 - gut.bmj.com
Objective A multicentre cohort follow-up study of a large number of patients with gastric
mucosa-associated lymphoid tissue (MALT) lymphoma was conducted to elucidate the long …

Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation

F Suarez, O Lortholary, O Hermine, M Lecuit - Blood, 2006 - ashpublications.org
Non-Hodgkin lymphomas develop from nodal and extranodal lymphoid tissues. A distinct
subset of extranodal lymphomas arising from B cells of the marginal zone (MZ) of mucosa …

Helicobacter pylori: perspectives and time trends

P Malfertheiner, A Link, M Selgrad - Nature reviews Gastroenterology & …, 2014 - nature.com
The discovery of Helicobacter pylori three decades ago is a modern medical success story. It
markedly changed our understanding of the pathophysiology of gastroduodenal diseases …

Differential requirement for Malt1 in T and B cell antigen receptor signaling

J Ruland, GS Duncan, A Wakeham, TW Mak - Immunity, 2003 - cell.com
Abstract The translocation t (11; 18)(q21; q21) involving MALT1 is the most common
chromosomal abnormality in lymphomas of mucosa-associated lymphoid tissue. Although …

MALT lymphoma: from morphology to molecules

PG Isaacson, MQ Du - Nature Reviews Cancer, 2004 - nature.com
Hints that the growth of some lymphomas is stimulated by bacterial antigens and can be
controlled by treatment with antibiotics first emerged in the 1970s. Subsequently, a specific …