Recombinant ASF live attenuated virus strains as experimental vaccine candidates
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical
area of the Eastern Hemisphere, from Central Europe to East and Southeast Asia, and …
area of the Eastern Hemisphere, from Central Europe to East and Southeast Asia, and …
Avian influenza virus tropism in humans
An influenza pandemic happens when a novel influenza A virus is able to infect and transmit
efficiently to a new, distinct host species. Although the exact timing of pandemics is …
efficiently to a new, distinct host species. Although the exact timing of pandemics is …
Deletion of the A137R gene from the pandemic strain of African swine fever virus attenuates the strain and offers protection against the virulent pandemic virus
African swine fever virus (ASFV) is causing a devastating pandemic in domestic and wild
swine within an extended geographical area from Central Europe to East Asia, resulting in …
swine within an extended geographical area from Central Europe to East Asia, resulting in …
African swine fever virus MGF360-11L negatively regulates cGAS-STING-mediated inhibition of type I interferon production
K Yang, Y Xue, H Niu, C Shi, M Cheng, J Wang… - Veterinary …, 2022 - Springer
The type I interferon (IFN-I) signaling pathway is an important part of the innate immune
response and plays a vital role in controlling and eliminating pathogens. African swine fever …
response and plays a vital role in controlling and eliminating pathogens. African swine fever …
African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation
Y Liu, Z Shen, Z Xie, Y Song, Y Li… - Proceedings of the …, 2023 - National Acad Sciences
African swine fever virus (ASFV) is a large, double-stranded DNA virus that causes a fatal
disease in pigs, posing a threat to the global pig industry. Whereas some ASFV proteins …
disease in pigs, posing a threat to the global pig industry. Whereas some ASFV proteins …
African swine fever virus MGF505-11R inhibits type I interferon production by negatively regulating the cGAS-STING-mediated signaling pathway
K Yang, Q Huang, R Wang, Y Zeng, M Cheng… - Veterinary …, 2021 - Elsevier
African swine fever (ASF) is an acute, hemorrhagic, and highly contact infectious disease
caused by African swine fever virus (ASFV) infecting domestic pigs or wild boars, the …
caused by African swine fever virus (ASFV) infecting domestic pigs or wild boars, the …
Combinational deletions of MGF360-9L and MGF505-7R attenuated highly virulent African swine fever virus and conferred protection against homologous challenge
M Ding, W Dang, H Liu, F Xu, H Huang… - Journal of …, 2022 - Am Soc Microbiol
Multigene family (MGF) gene products are increasingly reported to be implicated in African
swine fever virus (ASFV) virulence and attenuation of host defenses, among which the …
swine fever virus (ASFV) virulence and attenuation of host defenses, among which the …
Evaluation of the deletion of MGF110-5L-6L on swine virulence from the pandemic strain of African swine fever virus and use as a DIVA marker in vaccine candidate …
African swine fever virus (ASFV) is responsible for an ongoing pandemic that is affecting
central Europe, Asia, and recently the Dominican Republic, the first report of the disease in …
central Europe, Asia, and recently the Dominican Republic, the first report of the disease in …
Differential effect of deleting members of African swine fever virus multigene families 360 and 505 from the genotype II Georgia 2007/1 isolate on virus replication …
A Rathakrishnan, S Connell, V Petrovan… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus multigene family (MGF) 360 and 505 genes have roles in
suppressing the type I interferon response and in virulence in pigs. The role of the individual …
suppressing the type I interferon response and in virulence in pigs. The role of the individual …
The 2022 Outbreaks of African Swine Fever Virus Demonstrate the First Report of Genotype II in Ghana
E Spinard, A Rai, J Osei-Bonsu, V O'Donnell… - Viruses, 2023 - mdpi.com
African swine fever (ASF) is a lethal disease of domestic pigs that has been causing
outbreaks for over a century in Africa ever since its first discovery in 1921. Since 1957, there …
outbreaks for over a century in Africa ever since its first discovery in 1921. Since 1957, there …