Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

R Nahar, W Zhai, T Zhang, A Takano, AJ Khng… - Nature …, 2018 - nature.com
EGFR-mutant lung adenocarcinomas (LUAD) display diverse clinical trajectories and are
characterized by rapid but short-lived responses to EGFR tyrosine kinase inhibitors (TKIs) …

The Hidden Pathogenesis of CML: Is BCR-ABL1 the First Event?

N Shanmuganathan, S Branford - Current Hematologic Malignancy …, 2019 - Springer
Abstract Purpose of Review Identification of the BCR-ABL1 fusion oncogene in patients
diagnosed with chronic myeloid leukemia (CML) led to the development of targeted therapy …

Non-Ph variants in CML: guilty drivers?

S Mustjoki - Blood, The Journal of the American Society of …, 2018 - ashpublications.org
In this issue of Blood, Branford et al report that somatic variants other than BCR-ABL1 are
frequently found in patients with newly diagnosed chronic myeloid leukemia (CML). 1 …