Extended criteria donors in liver transplantation

I Vodkin, A Kuo - Clinics in liver disease, 2017 - liver.theclinics.com
Mortality rates on the liver transplant waiting list are increasing. 1 The shortage of organs
has resulted in higher utilization of extended criteria donors (ECDs), with centers pushing …

[PDF][PDF] Nonalcoholic steatohepatitis after liver transplantation

TG Cotter, M Charlton - Liver Transplantation, 2020 - Wiley Online Library
Currently, nonalcoholic steatohepatitis (NASH) is the second leading indication for liver
transplantation (LT), behind alcohol‐related liver disease. After transplant, both recurrent …

Extended-criteria donors in liver transplantation Part II: reviewing the impact of extended-criteria donors on the complications and outcomes of liver transplantation

B Nemes, G Gámán, WG Polak, F Gelley… - Expert review of …, 2016 - Taylor & Francis
Extended-criteria donors (ECDs) have an impact on early allograft dysfunction (EAD), biliary
complications, relapse of hepatitis C virus (HCV), and survivals. Early allograft dysfunction …

Molecular responses to ischemia and reperfusion in the liver

KM Quesnelle, PV Bystrom, LH Toledo-Pereyra - Archives of toxicology, 2015 - Springer
Ischemia/reperfusion (IR) injury occurs when oxygen is rapidly reintroduced into ischemic
tissue, resulting in cell death and necrotic tissue damage. This is a major concern during …

[HTML][HTML] Donation after cardiac death liver transplant recipients have an increased frequency of acute kidney injury

JA Leithead, L Tariciotti, B Gunson, A Holt… - American Journal of …, 2012 - Elsevier
Donation after cardiac death (DCD) liver transplantation is associated with an increased
frequency of hepato-biliary complications. The implications for renal function have not been …

Review of randomized clinical trials of donor management and organ preservation in deceased donors: opportunities and issues

GS Dikdan, C Mora-Esteves, B Koneru - Transplantation, 2012 - journals.lww.com
Given the static number of deceased donors, improvements in donor management and
organ preservation to increase the number and quality of organs transplanted per donor are …

Nonalcoholic fatty liver disease: key considerations before and after liver transplantation

YA Patel, CL Berg, CA Moylan - Digestive diseases and sciences, 2016 - Springer
Nonalcoholic fatty liver disease (NAFLD) is the most common etiology of chronic liver
disease in developed countries and is on trajectory to become the leading indication for liver …

How to preserve steatotic liver grafts for transplantation

D Patrono, N De Stefano, E Vissio, AL Apostu… - Journal of Clinical …, 2023 - mdpi.com
Liver allograft steatosis is a significant risk factor for postoperative graft dysfunction and has
been associated with inferior patient and graft survival, particularly in the case of moderate …

Hepatic ischemia reperfusion injury is associated with acute kidney injury following donation after brain death liver transplantation

JA Leithead, MJ Armstrong, C Corbett… - Transplant …, 2013 - Wiley Online Library
Donation after cardiac death liver transplant recipients have an increased frequency of acute
kidney injury (AKI). This suggests that hepatic ischemia‐reperfusion injury may play a critical …

Ischemic preconditioning induces autophagy and limits necrosis in human recipients of fatty liver grafts, decreasing the incidence of rejection episodes

D Degli Esposti, M Sebagh, P Pham, M Reffas… - Cell death & …, 2011 - nature.com
Whether ischemic preconditioning (IP) reduces ischemia/reperfusion (I/R) injury in human
normal and fatty livers remains controversial. We compared two independent groups of liver …