Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Role of traditional Chinese medicine in bone regeneration and osteoporosis

Z Peng, R Xu, Q You - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
According to World Health Organization (WHO), osteoporosis is a systematic bone disability
marked by reduced bone mass and microarchitectural degeneration of osseous cells, which …

Therapeutic anabolic and anticatabolic benefits of natural Chinese medicines for the treatment of osteoporosis

J He, X Li, Z Wang, S Bennett, K Chen, Z Xiao… - Frontiers in …, 2019 - frontiersin.org
Osteoporosis is a bone disease characterized by increasing osseous fragility and fracture
due to the reduced bone mass and microstructural degradation. Primary pharmacological …

Rehmanniae Radix in osteoporosis: a review of traditional Chinese medicinal uses, phytochemistry, pharmacokinetics and pharmacology

C Liu, R Ma, L Wang, R Zhu, H Liu, Y Guo… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Emerging clinical usage and pharmacological effects have
been achieved in using Rehmanniae Radix either singly or in combination with other herbs …

Anti-inflammatory and antioxidant traditional Chinese Medicine in treatment and prevention of osteoporosis

Q Li, C Tian, X Liu, D Li, H Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
A metabolic bone disorder called osteoporosis is characterized by decreased bone mass
and compromised microarchitecture. This condition can deteriorate bones and raise the risk …

Natural products from Chinese medicines with potential benefits to bone health

CT Che, MS Wong, CWK Lam - Molecules, 2016 - mdpi.com
Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass
and microstructure, leading to reduced bone strength and increased risk of fracture. It is …

Anti-osteoporosis effects of osteoking via reducing reactive oxygen species

D Qin, H Zhang, H Zhang, T Sun, H Zhao… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Osteoking is a Traditional Chinese Medicine consisting of
seven types of medicinal herbs originated from Yi nationality and has been used in clinic to …

Jiangu granules ameliorate postmenopausal osteoporosis via rectifying bone homeostasis imbalance: A network pharmacology analysis based on multi-omics …

C Li, X Lin, Q Lin, Y Lin, H Lin - Phytomedicine, 2024 - Elsevier
Background Postmenopausal osteoporosis (PMOP) is a series of reactions to bone
homeostasis dysregulation mediated by estrogen deficiency in elderly women. Jiangu …

Advances in the discovery of cathepsin K inhibitors on bone resorption

J Lu, M Wang, Z Wang, Z Fu, A Lu… - Journal of enzyme …, 2018 - Taylor & Francis
Abstract Cathepsin K (Cat K), highly expressed in osteoclasts, is a cysteine protease
member of the cathepsin lysosomal protease family and has been of increasing interest as a …

Gastrodin: an ancient Chinese herbal medicine as a source for anti-osteoporosis agents via reducing reactive oxygen species

Q Huang, J Shi, B Gao, HY Zhang, J Fan, XJ Li, JZ Fan… - Bone, 2015 - Elsevier
Increased levels of reactive oxygen species (ROS) are a crucial pathogenic factor of
osteoporosis. Gastrodin, isolated from the traditional Chinese herbal agent Gastrodia elata …