[HTML][HTML] Goblet cells: multifaceted players in immunity at mucosal surfaces

KA Knoop, RD Newberry - Mucosal immunology, 2018 - Elsevier
Goblet cells (GCs) are specialized epithelial cells that line multiple mucosal surfaces and
have a well-appreciated role in barrier maintenance through the secretion of mucus …

Tumor-infiltrating dendritic cells in cancer pathogenesis

JM Tran Janco, P Lamichhane… - The Journal of …, 2015 - journals.aai.org
Dendritic cells (DCs) play a pivotal role in the tumor microenvironment, which is known to
affect disease progression in many human malignancies. Infiltration by mature, active DCs …

Lactate-dependent regulation of immune responses by dendritic cells and macrophages

I Manoharan, PD Prasad, M Thangaraju… - Frontiers in …, 2021 - frontiersin.org
For decades, lactate has been considered an innocuous bystander metabolite of cellular
metabolism. However, emerging studies show that lactate acts as a complex …

How tolerogenic dendritic cells induce regulatory T cells

RA Maldonado, UH von Andrian - Advances in immunology, 2010 - Elsevier
Since their discovery by Steinman and Cohn in 1973, dendritic cells (DCs) have become
increasingly recognized for their crucial role as regulators of innate and adaptive immunity …

Dendritic cell control of tolerogenic responses

S Manicassamy, B Pulendran - Immunological reviews, 2011 - Wiley Online Library
One of the most fundamental problems in immunology is the seemingly schizophrenic ability
of the immune system to launch robust immunity against pathogens, while acquiring and …

Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose

A De Titta, M Ballester, Z Julier… - Proceedings of the …, 2013 - National Acad Sciences
In subunit vaccines, strong CD8+ T-cell responses are desired, yet they are elusive at
reasonable adjuvant doses. We show that targeting adjuvant to the lymph node (LN) via …

Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12

N Schmitt, R Morita, L Bourdery, SE Bentebibel… - Immunity, 2009 - cell.com
T follicular helper (Tfh) cells help development of antibody responses via interleukin-21 (IL-
21). Here we show that activated human dendritic cells (DCs) induced naive CD4+ T cells to …

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16-monocyte subsets

P Ancuta, KY Liu, V Misra, VS Wacleche, A Gosselin… - BMC genomics, 2009 - Springer
Background Human peripheral blood monocytes (Mo) consist of subsets distinguished by
expression of CD16 (FCγRIII) and chemokine receptors. Classical CD16-Mo express CCR2 …

Functional specialization of skin dendritic cell subsets in regulating T cell responses

BE Clausen, P Stoitzner - Frontiers in immunology, 2015 - frontiersin.org
Dendritic cells (DC) are a heterogeneous family of professional antigen-presenting cells
classically recognized as most potent inducers of adaptive immune responses. In this …

Features of the dendritic cell lineage.

RM Steinman, J Idoyaga - Immunological reviews, 2010 - search.ebscohost.com
The article examines various criteria and nomenclature of human dendritic cells (DC). DC
lineage is based on distinct morphology, biomarkers and gene expression profiles, which …