Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

A growing body of evidence from multiple areas proposes that periodontal disease,
accompanied by oral inflammation and pathological changes in the microbiome, induces gut …

Objective Estrogen related receptor α (ERRα) occupies a central node in the transcriptional
control of energy metabolism, including in skeletal muscle, but whether modulation of its …

The number of studies using skeletal muscle (SkM) cell culture models to study exercise in
vitro are rapidly expanding. Progressively, more comprehensive analysis methods, such as …

The notion that mobile units of nucleic acid known as transposable elements can operate as
genomic controlling elements was put forward over six decades ago,. However, it was not …

Hypomorphic Glucose 6-P dehydrogenase (G6PD) alleles, which cause G6PD deficiency,
affect around one in twenty people worldwide. The high incidence of G6PD deficiency may …

Exercise-like electrical pulse stimulation (EL-EPS) of myotubes mimics many key
physiological changes induced by in vivo exercise. Besides enabling intracellular research …

Many of the molecular and cellular mechanisms discovered to regulate skeletal muscle
hypertrophy were first identified using the rodent synergist ablation model. This model …

The application of exercise-like electrical pulse simulation (EL-EPS) has become a widely
used exercise mimetic in vitro. EL-EPS produces similar physiological responses as in vivo …

Skeletal muscles comprise more than a third of human body mass and critically contribute to
regulation of body metabolism. Chronic inactivity reduces metabolic activity and functional …