[HTML][HTML] Single-cell deconvolution of fibroblast heterogeneity in mouse pulmonary fibrosis

T Xie, Y Wang, N Deng, G Huang, F Taghavifar… - Cell reports, 2018 - cell.com
Fibroblast heterogeneity has long been recognized in mouse and human lungs,
homeostasis, and disease states. However, there is no common consensus on fibroblast …

Genetic predisposition to sarcoidosis

SY Liao, T Fingerlin, L Maier - Journal of Autoimmunity, 2023 - Elsevier
Sarcoidosis is a complex systemic disease with clinical heterogeneity based on varying
phenotypes and natural history. The detailed etiology of sarcoidosis remains unknown, but …

Performance evaluation and online realization of data-driven normalization methods used in LC/MS based untargeted metabolomics analysis

B Li, J Tang, Q Yang, X Cui, S Li, S Chen, Q Cao… - Scientific reports, 2016 - nature.com
In untargeted metabolomics analysis, several factors (eg, unwanted experimental &
biological variations and technical errors) may hamper the identification of differential …

Identification of immune-relevant factors conferring sarcoidosis genetic risk

A Fischer, D Ellinghaus, M Nutsua… - American journal of …, 2015 - atsjournals.org
Rationale: Genetic variation plays a significant role in the etiology of sarcoidosis. However,
only a small fraction of its heritability has been explained so far. Objectives: To define further …

Transcriptome profiles in sarcoidosis and their potential role in disease prediction

JC Schupp, M Vukmirovic, N Kaminski… - Current opinion in …, 2017 - journals.lww.com
Transcriptome profiles in sarcoidosis and their potential ro... : Current Opinion in Pulmonary
Medicine Transcriptome profiles in sarcoidosis and their potential role in disease prediction …

Upregulation of interleukin-33 and thymic stromal lymphopoietin levels in the lungs of idiopathic pulmonary fibrosis

JU Lee, HS Chang, HJ Lee, CA Jung, DJ Bae… - BMC pulmonary …, 2017 - Springer
Background Innate T helper type 2 (Th2) immune responses mediated by interleukin (IL)-33,
thymic stromal lymphopoietin (TSLP), and IL-25 have been shown to play an important role …

Ninjurin1 plays a crucial role in pulmonary fibrosis by promoting interaction between macrophages and alveolar epithelial cells

S Choi, JK Woo, YS Jang, JH Kang, JI Hwang… - Scientific reports, 2018 - nature.com
The transmembrane nerve injury-induced protein 1 (Ninjurin1 or Ninj1) is involved in
progressing inflammatory diseases. In this study, we aimed to investigate a novel function of …

A functional proteomics approach to the comprehension of sarcoidosis

C Landi, E Bargagli, A Carleo, L Bianchi, A Gagliardi… - Journal of …, 2015 - Elsevier
Pulmonary sarcoidosis (Sar) is an idiopathic disease histologically typified by non-caseating
epitheliod cell sarcoid granulomas. A cohort of 37 Sar patients with chronic persistent …

Genetic Programs Between Steroid-Sensitive and Steroid-Insensitive Interstitial Lung Disease

Y Lu, K Tang, S Wang, P Gao, Z Tian, M Wang, J Chen… - Inflammation, 2023 - Springer
The effectiveness of corticosteroids (GCs) varies greatly in interstitial lung diseases (ILDs). In
this study, we aimed to compare the gene expression profiles of patients with cryptogenic …

Identification of common signatures in idiopathic pulmonary fibrosis and lung cancer using gene expression modeling

D Leng, J Yi, M Xiang, H Zhao, Y Zhang - BMC cancer, 2020 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is associated with an increased risk for lung
cancer, but the underlying mechanisms driving malignant transformation remain largely …