Mechanics of morphological instabilities and surface wrinkling in soft materials: a review
Morphological instabilities and surface wrinkling of soft materials such as gels and biological
tissues are of growing interest to a number of academic disciplines including soft …
tissues are of growing interest to a number of academic disciplines including soft …
Airway smooth muscle function in asthma
Known to have affected around 340 million people across the world in 2018, asthma is a
prevalent chronic inflammatory disease of the airways. The symptoms such as wheezing …
prevalent chronic inflammatory disease of the airways. The symptoms such as wheezing …
Surface wrinkling of mucosa induced by volumetric growth: theory, simulation and experiment
Mechanics of living tissues focusing on the relationships between growth, morphology and
function is not only of theoretical interest but can also be useful for diagnosis of certain …
function is not only of theoretical interest but can also be useful for diagnosis of certain …
Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo
DC Adams, LP Hariri, AJ Miller, Y Wang… - Science translational …, 2016 - science.org
The inability to visualize airway smooth muscle (ASM) cells in vivo is a major obstacle in
understanding their role in normal physiology and diseases. At present, there is no imaging …
understanding their role in normal physiology and diseases. At present, there is no imaging …
Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling
Asthma is an obstructive airway disease, with a heterogeneous and multifactorial
pathogenesis. Although generally considered to be a disease principally driven by chronic …
pathogenesis. Although generally considered to be a disease principally driven by chronic …
Volumetric optical frequency domain imaging of pulmonary pathology with precise correlation to histopathology
LP Hariri, MB Applegate, M Mino-Kenudson, EJ Mark… - Chest, 2013 - Elsevier
Background Lung cancer is the leading cause of cancer-related mortality. Radiology and
bronchoscopy techniques do not have the necessary resolution to evaluate lung lesions on …
bronchoscopy techniques do not have the necessary resolution to evaluate lung lesions on …
Growth and surface folding of esophageal mucosa: a biomechanical model
Mucosal folding in such biological vessels as esophagus and airway is essential to their
physiological functions and can be affected by some diseases, eg, inflammation, edema …
physiological functions and can be affected by some diseases, eg, inflammation, edema …
Airway narrowing and bronchodilation to deep inspiration in bronchial segments from subjects with and without reported asthma
PB Noble, RL Jones, A Cairncross… - Journal of applied …, 2013 - journals.physiology.org
The present study presents preliminary findings on how structural/functional abnormalities of
the airway wall relate to excessive airway narrowing and reduced bronchodilatory response …
the airway wall relate to excessive airway narrowing and reduced bronchodilatory response …
Patient-specific airway wall remodeling in chronic lung disease
M Eskandari, WG Kuschner, E Kuhl - Annals of biomedical engineering, 2015 - Springer
Chronic lung disease affects more than a quarter of the adult population; yet, the mechanics
of the airways are poorly understood. The pathophysiology of chronic lung disease is …
of the airways are poorly understood. The pathophysiology of chronic lung disease is …
Models to study airway smooth muscle contraction in vivo, ex vivo and in vitro: implications in understanding asthma
Asthma is a chronic obstructive airway disease characterised by airway
hyperresponsiveness (AHR) and airway wall remodelling. The effector of airway narrowing …
hyperresponsiveness (AHR) and airway wall remodelling. The effector of airway narrowing …