DNAzyme-based biosensors: Immobilization strategies, applications, and future prospective

S Khan, B Burciu, CDM Filipe, Y Li, K Dellinger… - Acs Nano, 2021 - ACS Publications
Since their discovery almost three decades ago, DNAzymes have been used extensively in
biosensing. Depending on the type of DNAzyme being used, these functional …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

miRNAs as potential biomarkers for viral hepatitis B and C

D Loureiro, I Tout, S Narguet, SM Benazzouz… - Viruses, 2020 - mdpi.com
Around 257 million people are living with hepatitis B virus (HBV) chronic infection and 71
million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead …

Serum miRNA signature in rheumatoid arthritis and “at-risk individuals”

CC Cunningham, S Wade, A Floudas, C Orr… - Frontiers in …, 2021 - frontiersin.org
Background MicroRNAs (miRNAs) are small non-coding RNAs which have been implicated
as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines …

Circulating small extracellular vesicles microRNAs plus CA-125 for treatment stratification in advanced ovarian cancer

X Zhou, M Liu, L Sun, Y Cao, S Tan, G Luo… - Journal of Translational …, 2023 - Springer
Background No residual disease (R0 resection) after debulking surgery is the most critical
independent prognostic factor for advanced ovarian cancer (AOC). There is an unmet …

Non-coding RNA-based biosensors for early detection of liver cancer

S Falahi, HA Rafiee-Pour, M Zarejousheghani… - Biomedicines, 2021 - mdpi.com
Primary liver cancer is an aggressive, lethal malignancy that ranks as the fourth leading
cause of cancer-related death worldwide. Its 5-year mortality rate is estimated to be more …

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

SZ Bahojb Mahdavi, A Jebelli… - Medicinal Research …, 2024 - Wiley Online Library
Infections caused by viruses as the smallest infectious agents, pose a major threat to global
public health. Viral infections utilize different host mechanisms to facilitate their own …

Induction of microRNA hsa-let-7d-5p, and repression of HMGA2, contribute protection against lipid accumulation in macrophage 'foam'cells

RJ Lightbody, JMW Taylor, Y Dempsie… - Biochimica et Biophysica …, 2021 - Elsevier
Accumulation of excess cholesterol and cholesteryl ester in macrophage 'foam'cells within
the arterial intima characterises early 'fatty streak'atherosclerotic lesions, and is …

The potential diagnostic accuracy of let-7 family for cancer: A meta-analysis

WT Zhang, GX Zhang, SS Gao - Technology in cancer …, 2021 - journals.sagepub.com
Background: Cancer is a global public health problem affecting human health. Early stage of
cancer diagnosis, when it is not too large and has not spread is important for successful …

Exploring the role of non-coding RNAs in atrial septal defect pathogenesis: A systematic review

Z AmiRsardari, A Gholipour, Z Khajali, M Maleki… - Plos one, 2024 - journals.plos.org
Background Extensive research has recognized the significant roles of non-coding RNAs
(ncRNAs) in various cellular pathophysiological processes and their association with …