The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

The gut microbiota encompasses a diverse community of bacteria that carry out various
functions influencing the overall health of the host. These comprise nutrient metabolism …

Fecal microbial community changes are associated with numerous disease states, including
cardiovascular disease (CVD). However, such data are merely associative. A causal …

A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …

Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …

Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and
carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several …

Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …

Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …