Advances in imaging in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer

X Kong, Q Zhang, X Wu, T Zou, J Duan, S Song… - Frontiers in …, 2022 - frontiersin.org
Neoadjuvant chemotherapy (NAC) is increasingly widely used in breast cancer treatment,
and accurate evaluation of its response provides essential information for treatment and …

[HTML][HTML] Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients

J Kukačka, S Metz, C Dehner, A Muckenhuber… - Photoacoustics, 2022 - Elsevier
Background Since the initial breast transillumination almost a century ago, breast cancer
imaging using light has been considered in different implementations aiming to improve …

Hybrid time-domain and continuous-wave diffuse optical tomography instrument with concurrent, clinical magnetic resonance imaging for breast cancer imaging

JM Cochran, DR Busch, L Lin… - … of biomedical optics, 2019 - spiedigitallibrary.org
Diffuse optical tomography has demonstrated significant potential for clinical utility in the
diagnosis and prognosis of breast cancer, and its use in combination with other structural …

Diffuse optical spectroscopic imaging reveals distinct early breast tumor hemodynamic responses to metronomic and maximum tolerated dose regimens

A Tank, HM Peterson, V Pera, S Tabassum… - Breast cancer …, 2020 - Springer
Background Breast cancer patients with early-stage disease are increasingly administered
neoadjuvant chemotherapy (NAC) to downstage their tumors prior to surgery. In this setting …

A scalable, multi-wavelength, broad bandwidth frequency-domain near-infrared spectroscopy platform for real-time quantitative tissue optical imaging

RA Stillwell, VJ Kitsmiller, AY Wei, A Chong… - Biomedical optics …, 2021 - opg.optica.org
Frequency-domain near-infrared spectroscopy (FD-NIRS) provides quantitative noninvasive
measurements of tissue optical absorption and scattering, as well as a safe and accurate …

Macroscopic fluorescence lifetime imaging for monitoring of drug–target engagement

M Ochoa, A Rudkouskaya, JT Smith, X Intes… - … Technologies: Volume 2, 2022 - Springer
Precision medicine promises to improve therapeutic efficacy while reducing adverse effects,
especially in oncology. However, despite great progresses in recent years, precision …

Compact fiber-free parallel-plane multi-wavelength diffuse optical tomography system for breast imaging

Y Wang, S Li, Y Wang, Q Yan, X Wang, Y Shen, Z Li… - Optics …, 2022 - opg.optica.org
To facilitate the clinical applicability of the diffuse optical inspection device, a compact multi-
wavelength diffuse optical tomography system for breast imaging (compact-DOTB) with a …

Changes in the tumor oxygenation but not in the tumor volume and tumor vascularization reflect early response of breast cancer to neoadjuvant chemotherapy

MV Pavlov, AP Bavrina, VI Plekhanov… - Breast Cancer …, 2023 - Springer
Background Breast cancer neoadjuvant chemotherapy (NACT) allows for assessing tumor
sensitivity to systemic treatment, planning adjuvant treatment and follow-up. However, a …

Early assessment window for predicting breast cancer neoadjuvant therapy using biomarkers, ultrasound, and diffuse optical tomography

Q Zhu, FO Ademuyiwa, C Young, C Appleton… - Breast cancer research …, 2021 - Springer
Purpose The purpose of the study was to assess the utility of tumor biomarkers, ultrasound
(US) and US-guided diffuse optical tomography (DOT) in early prediction of breast cancer …

Breast cancer differential diagnosis using diffuse optical spectroscopic imaging and regression with z-score normalized data

JM Cochran, A Leproux, DR Busch… - … of biomedical optics, 2021 - spiedigitallibrary.org
Significance: Current imaging paradigms for differential diagnosis of suspicious breast
lesions suffer from high false positive rates that force patients to undergo unnecessary …