Molecular Modeling Methods in the Development of Affine and Specific Protein-Binding Agents

SS Nasaev, AR Mukanov, IV Mishkorez… - Biochemistry …, 2024 - Springer
High-affinity and specific agents are widely applied in various areas, including diagnostics,
scientific research, and disease therapy (as drugs and drug delivery systems). It takes …

The diagnostic potentiality of the RNA aptamer against progesterone receptor isolated by crush and soak (CRUSOAK)-SELEX

R Presela, SS Prabu, ES Ch'ng, TH Tang, M Citartan - Microchimica Acta, 2024 - Springer
Aptamers are a class of molecular recognition elements that exhibit high binding affinity and
specificity against their respective targets. In view of the many advantages aptamers harbor …

" Stability and affinity evaluation of aptamers as a biorecognition system for testosterone and its analogs".

A Medina-Benítez, CA García-Alonso… - bioRxiv, 2024 - biorxiv.org
The present project results from the need to develop a biosensor for the detection of
testosterone and synthetic analogs in nutritional supplements. A biosensor is composed of …

Unraveling the complexity: Advanced methods in analyzing DNA, RNA, and protein interactions

ML Peixoto, E Madan - Advances in cancer research, 2024 - pubmed.ncbi.nlm.nih.gov
Exploring the intricate interplay within and between nucleic acids, as well as their
interactions with proteins, holds pivotal significance in unraveling the molecular complexities …

Fluorescence-Based Techniques for the Identification of Small Biomolecules

C Frederic - 2024 - scholarship.shu.edu
Understanding fluorescence-based methods for detecting small biomolecules is a crucial
area of focus in research investigations. Our studies focused on the challenge in two parts …

[引用][C] Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer

KD Tew, PB Fisher, E Madan, R Gogna - 2024 - Elsevier