Drug repurposing in cancer therapy: influence of patient's genetic background in breast cancer treatment

R Rodrigues, D Duarte, N Vale - International journal of molecular …, 2022 - mdpi.com
Cancer is among the leading causes of death worldwide and it is estimated that in 2040
more than 29 million people will be diagnosed with some type of cancer. The most prevalent …

Engineering strategies for broad application of TCR-T-and CAR-T-cell therapies

K Watanabe, H Nishikawa - International Immunology, 2021 - academic.oup.com
Adoptive-cell therapy, including the transfer of tumor-infiltrating T lymphocytes after in vitro
expansion or T cells redirected to tumor antigens using antigen-specific transgenic T-cell …

Study designs for clinical trials applied to personalised medicine: a scoping review

C Superchi, FB Bouvier, C Gerardi, M Carmona… - BMJ open, 2022 - bmjopen.bmj.com
Objective Personalised medicine (PM) allows treating patients based on their individual
demographic, genomic or biological characteristics for tailoring the 'right treatment for the …

Drug repurposing for personalized medicine.

J Hora, N Rambhia, I Mani - Progress in Molecular Biology and …, 2024 - europepmc.org
Personalized medicine has emerged as a revolutionary approach to healthcare in the 21st
century. By understanding a patient's unique genetic and biological characteristics, it aims to …

[引用][C] 斑马鱼肌肉坏死模型的伊文思蓝活体成像: 一种新的研究坏死亲和性对比剂的平台

尧林鹏, 杨君, 杨荣, 薛星, 陈峰 - 分子影像学杂志, 2023 - j-fzyx.com
目的探讨制作斑马鱼肌肉坏死模型的可行性, 并应用此模型进行伊文思蓝(EBD)
活体成像以研究其坏死亲和特性. 方法采用显微注射泵注射10 nL 无水酒精于3~ 7 d …

Targeted therapies and utility of the Lung-molGPA in non-small-cell lung cancer patients with brain metastases

B Cacho-Díaz, LD Cuapantécatl, YJ Garcilazo-Reyes… - Oncology, 2022 - karger.com
Introduction: Therapeutic advances have increased the survival of non-small-cell lung
cancer (NSCLC) patients as well as the lifetime risk of being diagnosed with brain …

In vivo fluorescence imaging of Evans Blue dye in zebrafish muscle necrosis model: a new platform for studying necrosis avid agents

YAO Linpeng, Y Jun, Y Rong, XUE Xing, C Feng - 分子影像学杂志, 2023 - j-fzyx.com
Objective To explore the feasibility of making a muscle necrosis model in zebrafish, and to
apply this model to investigate the necrosis affinity of Evans Blue dye (EBD) by in vivo …