Glioblastoma is the most common primary malignant brain tumor that is usually considered
fatal even with treatment. This is often a result for tumor to develop resistance. Regarding the …

Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults with poor
prognosis. Despite the current state of knowledge on its genetic characteristics, relatively …

The poor prognosis of glioblastoma (GBM) routinely treated with ionizing radiation (IR) has
been attributed to the relative radioresistance of glioma-initiating cells (GIC). Other studies …

Glioblastoma is the most common adult primary brain tumor and has a dismal median
survival. Radiation is a mainstay of treatment and significantly improves survival, yet …

Radioresistance observed in patients with colorectal cancer (CRC) may be related to the
presence of cancer stem cells (CSCs), but the underlying mechanism (s) remain unclear …

Glioblastoma (GBM) is a devastating cancer of the brain with an extremely poor prognosis.
For this reason, besides clinical and preclinical studies, novel in vitro models for the …

Glioblastoma (GBM) patients have dismal median survival even with the most rigorous
treatments currently available. Radiotherapy is the most effective non-surgical therapy for …

Radioresistance remains a major obstacle for the radiotherapy treatment of cancer. Previous
studies have demonstrated that the radioresistance of cancer is due to the existence of …

Gliomas are the most frequent type of tumor in the central nervous system, which exhibit
properties that make their treatment difficult, such as cellular infiltration, heterogeneity, and …

Gliomas originate from glial cells and are the most frequent primary brain tumors. High-
grade gliomas occur∼ 4 times more frequently than low-grade gliomas, are highly …