Simple Summary Glycolipid metabolic disorders (GLMDs) result from imbalances in
glycolipid levels, leading to various health issues, including obesity, diabetes, liver …

Neurodegenerative disorders (NDDs) have been prevalent for more than a decade, and the
number of individuals affected per year has increased exponentially. Among these NDDs …

Introduction Diabetic nephropathy (DN), a major complication of diabetes, presents with
poor clinical outcomes and affects patients throughout their lifetime. α-Methyltryptophan (α …

Abstract Exogenous microRNA-144 (miR-144) is considered as a potential biological drug
for gastric cancer because of its biological activity to inhibit the epithelial-mesenchymal …

Background Esophageal squamous cell carcinoma (ESCC) remains a significant challenge
in oncology due to its aggressive nature and heterogeneity. As one of the deadliest …

Diabetic kidney disease (DKD) is a global and severe complication that imposes a
significant burden on individual health, families, and society. Currently, the main treatment …

Background/Objectives: The mammalian target of the rapamycin (mTOR) signaling pathway
is a central regulator of cell growth, proliferation, metabolism, and survival. Dysregulation of …

Aims This study investigated the molecular mechanisms of placenta-specific protein 1
(PLAC1) in cervical cancer (CCa), aiming to elucidate its role in tumorigenesis through in …

Sirolimus (Sir) is widely used in organ transplant patients because it inhibits the mechanistic
target of rapamycin (mTOR) activity and suppresses the immune system. In addition, Sir …

Levodopa remains the primary treatment for Parkinson's disease (PD), yet its long-term use
has been associated with iron accumulation in the brain, a phenomenon linked to …