Virtually every eukaryotic cell has an endogenous circadian clock and a biological sex.
These cell-based clocks have been conceptualized as oscillators whose phase can be reset …

Under stressful condition, reproductive function is impaired due to the activation of various
components of the hypothalamic–pituitaryadrenal (HPA) axis, which can suppress the …

The subjective experience of stress leads to reproductive dysfunction in many species,
including rodents and humans. Stress effects on reproduction result from multilevel …

Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits
gonadotropin secretion in birds and mammals. To further understand its physiological roles …

A fundamental principle in reproductive neuroendocrinology is sex steroid feedback: steroid
hormones secreted by the gonads circulate back to the brain to regulate the neural circuits …

Ovarian steroids normally exert homeostatic negative feedback on GnRH release. During
sustained exposure to elevated estradiol in the late follicular phase of the reproductive cycle …

Identification of novel neurohormones that regulate the reproductive axis is essential for the
progress of neuroendocrinology. The decapeptide gonadotropin-releasing hormone (GnRH) …

The recent discovery that an RFamide termed gonadotropin-inhibitory hormone is likely to
be a hypophysiotrophic gonadotropin release-inhibiting hormone in birds has generated …

A hypothalamic neuropeptide, gonadotropin-releasing hormone (GnRH), is the primary
factor regulating gonadotropin secretion. An inhibitory hypothalamic neuropeptide for …

RFamide-related peptide-3 (RFRP-3) is known to inhibit the activity of GnRH neurons. It is
not yet clear whether its G protein-coupled receptors, GPR147 and GPR74, are present on …