[HTML][HTML] Protein translocation across the ER membrane

R Zimmermann, S Eyrisch, M Ahmad… - Biochimica et Biophysica …, 2011 - Elsevier
Protein translocation into the endoplasmic reticulum (ER) is the first and decisive step in the
biogenesis of most extracellular and many soluble organelle proteins in eukaryotic cells. It is …

RHYTHM—a server to predict the orientation of transmembrane helices in channels and membrane-coils

A Rose, S Lorenzen, A Goede, B Gruening… - Nucleic acids …, 2009 - academic.oup.com
RHYTHM is a web server that predicts buried versus exposed residues of helical membrane
proteins. Starting from a given protein sequence, secondary and tertiary structure …

Contribution of charged and polar residues for the formation of the E1–E2 heterodimer from hepatitis C virus

SA Jusoh, C Welsch, SWI Siu, RA Böckmann… - Journal of molecular …, 2010 - Springer
The transmembrane domains of the envelope glycoprotein E1 and E2 have crucial
multifunctional roles in the biogenesis of hepatitis C virus. We have performed molecular …

Predicting structural and functional properties of membrane proteins from protein sequence

J Metzger, NS Schaadt, S Hayat, V Helms - Annual Reports in …, 2011 - Elsevier
Integral transmembrane (TM) proteins are essential constituents of biological membranes
where they fulfill a variety of important cellular functions. Because of difficulties with …

In silico evaluation of the influence of the translocon on partitioning of membrane segments

D Tessier, S Laroum, B Duval, EM Rath, WB Church… - BMC …, 2014 - Springer
Background The locations of the TM segments inside the membrane proteins are the
consequence of a cascade of several events: the localizing of the nascent chain to the …

MINS2: Revisiting the molecular code for transmembrane-helix recognition by the Sec61 translocon

Y Park, V Helms - Bioinformatics, 2008 - academic.oup.com
To be fully functional, membrane proteins should not only fold, but also get inserted into the
membrane, which is mediated by the Sec61 translocon. Recent experimental studies have …

Multi-neighborhood search for discrimination of signal peptides and transmembrane segments

S Laroum, B Duval, D Tessier, JK Hao - … EvoBIO 2011, Torino, Italy, April 27 …, 2011 - Springer
A key step in study of biosynthesis of membrane proteins is to look for the code that could be
used to explain and predict which proteins would eventually be inserted in the membrane …

Membrane Protein Biogenesis in Saccharomyces cerevisiae

J Reithinger - 2013 - diva-portal.org
Membranes are hydrophobic barriers that define the outer boundaries and internal
compartments of living cells. Membrane proteins are the gates in these barriers, and they …

Computational systems biology methods for functional classification of membrane proteins and modeling of quorum sensing in Pseudomonas aeruginosa

NS Schaadt - 2013 - publikationen.sulb.uni-saarland.de
Due to the function of membrane proteins and the effort required for experimental
annotations, bioinformatical approaches to functionally classify uncharacterized sequences …

[PDF][PDF] Computational Systems Biology Methods

NS Schaadt - 2013 - scholar.archive.org
Due to the function of membrane proteins and the effort required for experimental
annotations, bioinformatical approaches to functionally classify uncharacterized sequences …