Mechanistic insight on the role of leukotriene receptors in ischemic–reperfusion injury

H Khan, A Gupta, TG Singh, A Kaur - Pharmacological Reports, 2021 - Springer
Leukotrienes (LT) are a class of inflammatory mediators produced by the 5-lipoxygenase (5-
LO) enzyme from arachidonic acid (AA). We discussed the various LT inhibitors and …

Oxidative stress during ovarian torsion in pediatric and adolescent patients: changing the perspective of the disease

AS Laganà, V Sofo, FM Salmeri… - … journal of fertility & …, 2015 - pmc.ncbi.nlm.nih.gov
Among the different causes of gynecological acute pelvic pain, ovarian torsion represents a
surgical emergency. It is a rare case in the pediatric/adolescent aged group that must be …

The protective effects of beta-carotene against ischemia/reperfusion injury in rat ovarian tissue

SA Karamese, E Toktay, D Unal, J Selli, M Karamese… - Acta histochemica, 2015 - Elsevier
Introduction Beta-carotene is a well-known antioxidant and precursor of Vitamin A that has a
preventative role in the oxidative damage process. Our aim was to investigate the possible …

Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion …

OA Afolabi, MA Hamed, DC Anyogu, DH Adeyemi… - Redox …, 2022 - Taylor & Francis
Background Oxidative damage is critical in the pathogenesis of ovarian
ischaemia/reperfusion (I/R) injury, and statins have been reported to exert antioxidant …

α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic …

F Odabasoglu, Z Halici, H Aygun, M Halici… - British Journal of …, 2011 - cambridge.org
α-Lipoic acid (ALA) has been termed the 'ideal'antioxidant, a readily absorbed and
bioavailable compound capable of scavenging a number of free radicals, and it has been …

Aliskiren–a promising strategy for ovarian ischemia/reperfusion injury protection in rats via RAAS

Y Bayir, E Cadirci, B Polat… - Gynecological …, 2016 - Taylor & Francis
The aim of this study was to evaluate the effects of aliskiren, direct renin inhibitor, as an
antioxidant and tissue protective agent and evaluate the molecular, biochemical, and …

Protective effects of lithium: a new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis

A Albayrak, Z Halici, B Polat, E Karakus… - International …, 2013 - Elsevier
Sepsis is the systemic response of an organism against microorganisms and toxins. Lithium
is a therapeutic agent used for bipolar disorder and neurodegenerative disease, and it …

Selenium has a protective effect on ischemia/reperfusion injury in a rat ovary model: biochemical and histopathologic evaluation

S Bozkurt, DC Arikan, EB Kurutas, H Sayar… - Journal of Pediatric …, 2012 - Elsevier
BACKGROUND/PURPOSE: The aim of the study was to evaluate the effects of selenium
(Se) on ischemia/reperfusion (I/R) injury in rat ovaries. METHODS: Thirty-five female …

Antioxidant effect of erdosteine and lipoic acid in ovarian ischemia–reperfusion injury

R Dokuyucu, A Karateke, H Gokce, RK Kurt… - European Journal of …, 2014 - Elsevier
Objective To investigate the effects of erdosteine and alpha lipoic acid (ALA) in a rat model
of ovarian ischaemia–reperfusion injury. Study design Forty-eight female Wistar albino rats …

Evaluation of selenium on kidney function following ischemic injury in rats; protective effects and antioxidant activity

A Hasanvand, A Abbaszadeh, S Darabi… - Journal of renal …, 2016 - pmc.ncbi.nlm.nih.gov
Introduction: Renal dysfunction is caused by ischemia-reperfusion (I/R) injury, which is a
common problem in kidney surgery or kidney transplantation. The human body consists of …