REVIEW Most higher organisms reproduce sexually, despite the automatic reproductive
advantage experienced by asexual variants. This implies the operation of selective forces …

▪ Abstract Translational control is a prevalent means of gene regulation during Drosophila
oogenesis and embryogenesis. Multiple maternal mRNAs are localized within the oocyte …

In 1975, a Greek letter nomenclature system was introduced to designate DNA polymerases
from mammalian cells (1). Ten years ago, progress in the biochemical analysis of eukaryotic …

A century of genetic studies of the meiotic process in Drosophila melanogaster females has
been greatly augmented by both modern molecular biology and major advances in cytology …

The genes okra and spindle-B act during meiosis in Drosophila to repair double-stranded
DNA breaks (DSBs) associated with meiotic recombination. Unexpectedly, mutations in …

In high-throughput functional genomic screens, each gene product is commonly assumed to
exhibit a singular biological function within a defined protein complex or pathway. In …

MEI-9 is the Drosophila homolog of the human structure-specific DNA endonuclease XPF.
Like XPF, MEI-9 functions in nucleotide excision repair and interstrand crosslink repair. MEI …

Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging
agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes …

The environment has profound effects on the expression of many traits and reaction norms
describe the expression dynamics of a trait across a broad range of environmental …

The segregation of homologous chromosomes from one another is the essence of meiosis.
In many organisms, accurate segregation is ensured by the formation of chiasmata resulting …