High‐aspect‐ratio nanostructured surfaces as biological metamaterials

SG Higgins, M Becce… - Advanced …, 2020 - Wiley Online Library
Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Review of wearable technologies and machine learning methodologies for systematic detection of mild traumatic brain injuries

W Schmid, Y Fan, T Chi, E Golanov… - Journal of neural …, 2021 - iopscience.iop.org
Mild traumatic brain injuries (mTBIs) are the most common type of brain injury. Timely
diagnosis of mTBI is crucial in making'go/no-go'decision in order to prevent repeated injury …

Multi-parametric functional imaging of cell cultures and tissues with a CMOS microelectrode array

J Abbott, A Mukherjee, W Wu, T Ye, HS Jung… - Lab on a Chip, 2022 - pubs.rsc.org
Electrode-based impedance and electrochemical measurements can provide cell-biology
information that is difficult to obtain using optical-microscopy techniques. Such electrical …

High-density electrical recording and impedance imaging with a multi-modal CMOS multi-electrode array chip

B Miccoli, CM Lopez, E Goikoetxea, J Putzeys… - Frontiers in …, 2019 - frontiersin.org
Multi-electrode arrays, both active or passive, emerged as ideal technologies to unveil
intricated electrophysiological dynamics of cells and tissues. Active MEAs, designed using …

Impedance characterization and modeling of subcellular to micro-sized electrodes with varying materials and PEDOT: PSS coating for bioelectrical interfaces

A Wang, D Jung, D Lee, H Wang - ACS Applied Electronic …, 2021 - ACS Publications
Electrode-to-cell/tissue interfaces with high biocompatibility, low impedance, and long-term
chemical and mechanical stability are of paramount importance in numerous biological and …

The next generation of hybrid microfluidic/integrated circuit chips: recent and upcoming advances in high-speed, high-throughput, and multifunctional lab-on-IC …

V Iyer, DA Issadore, F Aflatouni - Lab on a Chip, 2023 - pubs.rsc.org
Since the field's inception, pioneers in microfluidics have made significant progress towards
realizing complete lab-on-chip systems capable of sophisticated sample analysis and …

A CMOS multi-modal electrochemical and impedance cellular sensing array for massively paralleled exoelectrogen screening

SR Kumashi, D Jung, J Park, ST Sanz… - … Circuits and Systems, 2021 - ieeexplore.ieee.org
The paper presents a 256-pixel CMOS sensor array with in-pixel dual electrochemical and
impedance detection modalities for rapid, multi-dimensional characterization of …

Optical imaging approaches to monitor static and dynamic cell‐on‐chip platforms: A tutorial review

A Arandian, Z Bagheri, H Ehtesabi, S Najafi Nobar… - Small, 2019 - Wiley Online Library
Miniaturized laboratories on chip platforms play an important role in handling life sciences
studies. The platforms may contain static or dynamic biological cells. Examples are a fixed …

Multimodal integrated sensor platform for rapid biomarker detection

MA Al-Rawhani, C Hu, C Giagkoulovits… - IEEE Transactions …, 2019 - ieeexplore.ieee.org
Precision metabolomics and quantification for cost-effective rapid diagnosis of disease are
the key goals in personalized medicine and point-of-care testing. At present, patients are …

A CMOS 21 952-pixel multi-modal cell-based biosensor with four-point impedance sensing for holistic cellular characterization

D Jung, GV Junek, JS Park, SR Kumashi… - IEEE Journal of Solid …, 2021 - ieeexplore.ieee.org
This article presents a fully integrated multi-modal CMOS cellular sensor/stimulator array
chip with 21 952 pixels and 1568-pixel concurrent readouts, while each array pixel can be …