Membrane-initiated estrogen, androgen, and progesterone receptor signaling in health and disease

F Mauvais-Jarvis, CA Lange, ER Levin - Endocrine reviews, 2022 - academic.oup.com
Rapid effects of steroid hormones were discovered in the early 1950s, but the subject was
dominated in the 1970s by discoveries of estradiol and progesterone stimulating protein …

Metabolic and epigenetic regulation by estrogen in adipocytes

JI Bjune, PP Strømland, RÅ Jersin… - Frontiers in …, 2022 - frontiersin.org
Sex hormones contribute to differences between males and females in body fat distribution
and associated disease risk. Higher concentrations of estrogens are associated with a more …

Changes in abdominal subcutaneous adipose tissue phenotype following menopause is associated with increased visceral fat mass

J Abildgaard, T Ploug, E Al-Saoudi, T Wagner… - Scientific reports, 2021 - nature.com
Menopause is associated with a redistribution of adipose tissue towards central adiposity,
known to cause insulin resistance. In this cross-sectional study of 33 women between 45 …

Sex differences in brown adipose tissue function: sex hormones, glucocorticoids, and their crosstalk

K Kaikaew, A Grefhorst, JA Visser - Frontiers in endocrinology, 2021 - frontiersin.org
Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …

Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes

TM Moore, L Cheng, DM Wolf, J Ngo, M Segawa… - Nature …, 2022 - nature.com
Parkin, an E3 ubiquitin ligase, plays an essential role in mitochondrial quality control.
However, the mechanisms by which Parkin connects mitochondrial homeostasis with …

Mitochondrial regulation and white adipose tissue homeostasis

Q Zhu, YA An, PE Scherer - Trends in cell biology, 2022 - cell.com
The important role of mitochondria in the regulation of white adipose tissue (WAT)
remodeling and energy balance is increasingly appreciated. The remarkable heterogeneity …

Adipocyte metabolism and health after the menopause: The role of exercise

ML Marsh, MN Oliveira, VJ Vieira-Potter - Nutrients, 2023 - mdpi.com
Postmenopausal women represent an important target population in need of preventative
cardiometabolic approaches. The loss of estrogen following the menopause eliminates …

The role of persistent organic pollutants in obesity: a review of laboratory and epidemiological studies

J Aaseth, D Javorac, AB Djordjevic, Z Bulat, AV Skalny… - Toxics, 2022 - mdpi.com
Persistent organic pollutants (POPs) are considered as potential obesogens that may affect
adipose tissue development and functioning, thus promoting obesity. However, various …

Mechanism of Astragalus membranaceus Alleviating Acquired Hyperlipidemia Induced by High-Fat Diet through Regulating Lipid Metabolism

L Wang, W Zheng, J Yang, A Ali, H Qin - Nutrients, 2022 - mdpi.com
Astragalus membranaceus (AM) is a food and medicinal homologous plant. The current
research is aimed to investigate the beneficial effects and mechanisms of AM in treating …

FoxO transcription factors in mitochondrial homeostasis

Z Cheng - Biochemical Journal, 2022 - portlandpress.com
Mitochondria play essential roles in cellular energetics, biosynthesis, and signaling
transduction. Dysfunctional mitochondria have been implicated in different diseases such as …