Going viral: The role of mobile genetic elements in bacterial immunity

B Beamud, F Benz, D Bikard - Cell Host & Microbe, 2024 - cell.com
Bacteriophages and other mobile genetic elements (MGEs) pose a significant threat to
bacteria, subjecting them to constant attacks. In response, bacteria have evolved a …

Tail assembly interference is a common strategy in bacterial antiviral defenses

L He, L Miguel-Romero, JB Patkowski… - Nature …, 2024 - nature.com
Many bacterial immune systems recognize phage structural components to activate antiviral
responses, without inhibiting the function of the phage component. These systems can be …

Evolution and ecology of anti-defence systems in phages and plasmids

T Niault, S van Houte, E Westra, DC Swarts - Current Biology, 2025 - cell.com
Summary Prokaryotes (Bacteria and Archaea) encode a highly diversified arsenal of
defence systems that protect them against mobile genetic elements, such as phages and …

Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools

T Mahata, K Kanarek, MG Goren… - Nature …, 2024 - nature.com
The evolutionary arms race between bacteria and phages led to the emergence of bacterial
immune systems whose diversity and dynamics remain poorly understood. Here we use …

The role of rhizosphere phages in soil health

X Wang, Y Tang, X Yue, S Wang, K Yang… - FEMS Microbiology …, 2024 - academic.oup.com
Abstract While the One Health framework has emphasized the importance of soil
microbiomes for plant and human health, one of the most diverse and abundant groups …

Antiviral defence systems in the rumen microbiome

JS Sáenz, B Rios-Galicia, J Seifert - bioRxiv, 2024 - biorxiv.org
The continuous interaction between phages and their respective hosts has resulted in the
evolution of multiple bacterial immune mechanism. However, the diversity and prevalence of …

A widespread bacterial mobile genetic element encodes weapons against phages, bacteria, and eukaryotes

T Mahata, K Kanarek, MG Goren, E Bosis, U Qimron… - bioRxiv, 2023 - biorxiv.org
Bacteria are found in ongoing conflicts with rivals and predators, which lead to an
evolutionary arms race and the development of innate and adaptive immune systems …

Tailless and filamentous prophages are predominant in marine Vibrio

K Steensen, J Séneca, N Bartlau, XA Yu… - The ISME …, 2024 - academic.oup.com
Although tailed bacteriophages (phages) of the class Caudoviricetes are thought to
constitute the most abundant and ecologically relevant group of phages that can integrate …

[HTML][HTML] A phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite spread

CM Boyd, KD Seed - bioRxiv, 2024 - ncbi.nlm.nih.gov
ICP1, a lytic bacteriophage of Vibrio cholerae, is parasitized by phage satellites, PLEs,
which hijack ICP1 proteins for their own horizontal spread. PLEs' dependence on ICP1's …

Identification of a large cohort of Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria

N Kanhirun, A Blanc, A Aindow, M You, JD Antani… - bioRxiv, 2024 - biorxiv.org
ESKAPE pathogens cause most hospital-acquired infections globally and often carry
antibiotic resistance. Many of them have been the target of bacteriophage therapies …