Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …

Familial gastric cancer comprises at least three major syndromes: hereditary diffuse gastric
cancer, gastric adenocarcinoma and proximal polyposis of the stomach, and familial …

Cadherins are homophilic adhesion molecules with important functions in cell-cell adhesion,
tissue morphogenesis, and cancer. In epithelial cells, E-cadherin accumulates at areas of …

Long noncoding RNAs (lncRNAs) have emerged recently as major players in governing
fundamental biological processes, and many of which are altered in expression and likely to …

Background Gastric cancer is the second leading cause of cancer death and remains a
major clinical challenge due to poor prognosis and limited treatment options. Long …

E-cadherin and P-cadherin are major contributors to cell–cell adhesion in epithelial tissues,
playing pivotal roles in important morphogenetic and differentiation processes during …

In the context of cancer, E-cadherin has traditionally been categorized as a tumor
suppressor, given its essential role in the formation of proper intercellular junctions, and its …

Purpose The prognosis of gastric cancer (GC) is poor, and the molecular pathogenesis
players are vastly unknown. Surgery remains the primary option in GC treatment. The aim of …

Cadherins are calcium-binding proteins with a pivotal role in cell adhesion and tissue
homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are …

Gastric cancer is the third leading cause of cancer-related deaths and ranks as the fifth most
common cancer worldwide. Incidence and mortality differ depending on the geographical …